In this paper, a two level finite difference scheme of Crank-Nicholson type is constructed and used to numerically investigate nonlinear temperature distribution in biological tissues described by bioheat transfer equ...In this paper, a two level finite difference scheme of Crank-Nicholson type is constructed and used to numerically investigate nonlinear temperature distribution in biological tissues described by bioheat transfer equation of Pennes’ type. For the equation under consideration, the thermal conductivity is either depth-dependent or tem-perature-dependent, while blood perfusion is temperature-dependent. In both cases of depth- dependent and temperature-dependent thermal conductivity, it is shown that blood perfusion decreases the temperature of the living tissue. Our numerical simulations show that neither the localization nor the magnitude of peak tempera-ture is affected by surface temperature;however, the width of peak temperature increases with surface temperature.展开更多
Based on the Pennes’ bioheat transfer equation, a simplified one-dimensional bioheat transfer model of the cylindrical living tissues in the steady state has been set up for application in limb and whole body heat tr...Based on the Pennes’ bioheat transfer equation, a simplified one-dimensional bioheat transfer model of the cylindrical living tissues in the steady state has been set up for application in limb and whole body heat transfer studies, and by using the Bessel’s equation, its corresponding analytic solution has been derived in this paper. With the obtained analytic solution, the effects of the thermal conductivity, the blood perfusion, the metabolic heat generation, and the coefficient of heat transfer on the temperature distribution in living tissues are analyzed. The results show that the derived analytic solution is useful to easily and accurately study the thermal behavior of the biological system, and can be extended to such applications as parameter measurement, temperature field reconstruction and clinical treatment.展开更多
A basic bioheat transfer equation based upon porous medium model was derived by Wang et al. in 1993 to improve the Pennes equation in common use previously. A steady one-dimensional general analytical solution of this...A basic bioheat transfer equation based upon porous medium model was derived by Wang et al. in 1993 to improve the Pennes equation in common use previously. A steady one-dimensional general analytical solution of this new equation was given by Wang et al. later under the condition of constant coefficients and rectangular coordinates. This analytical solution compared well with experimental data. In order to expand the understanding of the new equation, an unsteady one-dimensional particular analytical solution展开更多
This paper deals with the study of heat transfer and thermal damage in triple layer skin tissue using fractional bioheat model. Here, we consider three types of heating viz. sinusoidal heat flux, constant temperature ...This paper deals with the study of heat transfer and thermal damage in triple layer skin tissue using fractional bioheat model. Here, we consider three types of heating viz. sinusoidal heat flux, constant temperature and constant heat flux heating on skin surface. An implicit finite difference scheme is obtained by approximating fractional time derivative by quadrature formula and space derivative by central difference formula. The temperature profiles and thermal damage in the skin tissue are obtained to study the effect of fractional parameter a on diffusion process for constant temperature and heat flux boundary heating on skin surface. A parametric study for sinusoidal heat flux at skin surface has also been made.展开更多
As a new developing field, the science of bioheat transfer is making its fundamental propositions and theories much more complete and thus postulates new concepts based on the new discovery and knowledge. In this note...As a new developing field, the science of bioheat transfer is making its fundamental propositions and theories much more complete and thus postulates new concepts based on the new discovery and knowledge. In this note, an important improvement on the previously developed thermal wave models of bioheat transfer (TWMBT) is given.展开更多
This paper presents a 2D simulation of transient heat transfer in the human eye using appropriate boundary conditions.The mathematical model governing bioheat transfer in the human eye is discussed and the existence a...This paper presents a 2D simulation of transient heat transfer in the human eye using appropriate boundary conditions.The mathematical model governing bioheat transfer in the human eye is discussed and the existence and uniqueness of the solution are proven.Four methods based on finite element method and nonoverlapping domain decomposition method to obtain transient heat transfer in the human eye are presented and described in details.After conducting numerous simulations using realistic parameters obtained from the open literature and after comparison with measurements reported by previous experimental studies,all proposed methods gave an accurate representation of transient heat transfer in the human eye.The results obtained by the domain decomposition of the human eye into four subdomains are found to be the closest to reality.展开更多
An algebraically explicit analytical solution with heat wave effect is derived for the non-Fourier bioheat transfer Chen-Holmes model. Besides its important theoreti-cal meaning (for example, to expand the understandi...An algebraically explicit analytical solution with heat wave effect is derived for the non-Fourier bioheat transfer Chen-Holmes model. Besides its important theoreti-cal meaning (for example, to expand the understanding of heat wave phenomena in living tissues), this analytical solu-tion is also valuable as the benchmark solution to check the numerical calculation and to develop various numerical computational approaches.展开更多
文摘In this paper, a two level finite difference scheme of Crank-Nicholson type is constructed and used to numerically investigate nonlinear temperature distribution in biological tissues described by bioheat transfer equation of Pennes’ type. For the equation under consideration, the thermal conductivity is either depth-dependent or tem-perature-dependent, while blood perfusion is temperature-dependent. In both cases of depth- dependent and temperature-dependent thermal conductivity, it is shown that blood perfusion decreases the temperature of the living tissue. Our numerical simulations show that neither the localization nor the magnitude of peak tempera-ture is affected by surface temperature;however, the width of peak temperature increases with surface temperature.
文摘Based on the Pennes’ bioheat transfer equation, a simplified one-dimensional bioheat transfer model of the cylindrical living tissues in the steady state has been set up for application in limb and whole body heat transfer studies, and by using the Bessel’s equation, its corresponding analytic solution has been derived in this paper. With the obtained analytic solution, the effects of the thermal conductivity, the blood perfusion, the metabolic heat generation, and the coefficient of heat transfer on the temperature distribution in living tissues are analyzed. The results show that the derived analytic solution is useful to easily and accurately study the thermal behavior of the biological system, and can be extended to such applications as parameter measurement, temperature field reconstruction and clinical treatment.
基金Project supported by the National Natural Science Foundation of China.
文摘A basic bioheat transfer equation based upon porous medium model was derived by Wang et al. in 1993 to improve the Pennes equation in common use previously. A steady one-dimensional general analytical solution of this new equation was given by Wang et al. later under the condition of constant coefficients and rectangular coordinates. This analytical solution compared well with experimental data. In order to expand the understanding of the new equation, an unsteady one-dimensional particular analytical solution
文摘This paper deals with the study of heat transfer and thermal damage in triple layer skin tissue using fractional bioheat model. Here, we consider three types of heating viz. sinusoidal heat flux, constant temperature and constant heat flux heating on skin surface. An implicit finite difference scheme is obtained by approximating fractional time derivative by quadrature formula and space derivative by central difference formula. The temperature profiles and thermal damage in the skin tissue are obtained to study the effect of fractional parameter a on diffusion process for constant temperature and heat flux boundary heating on skin surface. A parametric study for sinusoidal heat flux at skin surface has also been made.
文摘As a new developing field, the science of bioheat transfer is making its fundamental propositions and theories much more complete and thus postulates new concepts based on the new discovery and knowledge. In this note, an important improvement on the previously developed thermal wave models of bioheat transfer (TWMBT) is given.
文摘This paper presents a 2D simulation of transient heat transfer in the human eye using appropriate boundary conditions.The mathematical model governing bioheat transfer in the human eye is discussed and the existence and uniqueness of the solution are proven.Four methods based on finite element method and nonoverlapping domain decomposition method to obtain transient heat transfer in the human eye are presented and described in details.After conducting numerous simulations using realistic parameters obtained from the open literature and after comparison with measurements reported by previous experimental studies,all proposed methods gave an accurate representation of transient heat transfer in the human eye.The results obtained by the domain decomposition of the human eye into four subdomains are found to be the closest to reality.
基金This work was supported by the National Natural Science Foundation of China(Grant No.50246003 and its succeeding foundation)the Major State Basic Research Development Program of China(Grant No.G20000263).
文摘An algebraically explicit analytical solution with heat wave effect is derived for the non-Fourier bioheat transfer Chen-Holmes model. Besides its important theoreti-cal meaning (for example, to expand the understanding of heat wave phenomena in living tissues), this analytical solu-tion is also valuable as the benchmark solution to check the numerical calculation and to develop various numerical computational approaches.