Manual acupuncture is widely used for pain relief and stress control.Previous studies on acupuncture have shown its modulatory effects on the functional connectivity associated with one or a few preselected brain regi...Manual acupuncture is widely used for pain relief and stress control.Previous studies on acupuncture have shown its modulatory effects on the functional connectivity associated with one or a few preselected brain regions.To investigate how manual acupuncture modulates the organization of functional networks at a whole-brain level,we acupuncture at ST36 of a right leg to obtain electroencephalograph(EEG) signals.By coherence estimation,we determine the synchronizations between all pairwise combinations of EEG channels in three acupuncture states.The resulting synchronization matrices are converted into functional networks by applying a threshold,and the clustering coefficients and path lengths are computed as a function of threshold.The results show that acupuncture can increase functional connections and synchronizations between different brain areas.For a wide range of thresholds,the clustering coefficient during acupuncture and postacupuncture period is higher than that during the pre-acupuncture control period,whereas the characteristic path length is shorter.We provide further support for the presence of "small-world" network characteristics in functional networks by using acupuncture.These preliminary results highlight the beneficial modulations of functional connectivity by manual acupuncture,which could contribute to the understanding of the effects of acupuncture on the entire brain,as well as the neurophysiological mechanisms underlying acupuncture.Moreover,the proposed method may be a useful approach to the further investigation of the complexity of patterns of interrelations between EEG channels.展开更多
To investigate whether and how manual acupuncture(MA) modulates brain activities,we design an experiment where acupuncture at acupoint ST36 of the right leg is used to obtain electroencephalograph(EEG) signals in ...To investigate whether and how manual acupuncture(MA) modulates brain activities,we design an experiment where acupuncture at acupoint ST36 of the right leg is used to obtain electroencephalograph(EEG) signals in healthy subjects.We adopt the autoregressive(AR) Burg method to estimate the power spectrum of EEG signals and analyze the relative powers in delta(0 Hz-4 Hz),theta(4 Hz-8 Hz),alpha(8 Hz-13 Hz),and beta(13 Hz-30 Hz) bands.Our results show that MA at ST36 can significantly increase the EEG slow wave relative power(delta band) and reduce the fast wave relative powers(alpha and beta bands),while there are no statistical differences in theta band relative power between different acupuncture states.In order to quantify the ratio of slow to fast wave EEG activity,we compute the power ratio index.It is found that the MA can significantly increase the power ratio index,especially in frontal and central lobes.All the results highlight the modulation of brain activities with MA and may provide potential help for the clinical use of acupuncture.The proposed quantitative method of acupuncture signals may be further used to make MA more standardized.展开更多
As a convenient approach to the characterization of cerebral cortex electrical information, electroencephalograph (EEG) has potential clinical application in monitoring the acupuncture effects. In this paper, a meth...As a convenient approach to the characterization of cerebral cortex electrical information, electroencephalograph (EEG) has potential clinical application in monitoring the acupuncture effects. In this paper, a method composed of the mutual information method and Lempel-Ziv complexity method (MILZC) is proposed to investigate the effects of acupuncture on the complexity of information exchanges between different brain regions based on EEGs. In the experiments, eight subjects are manually acupunctured at 'Zusanli' acupuncture point (ST-36) with different frequencies (i.e., 50, 100, 150, and 200 times/min) and the EEGs are recorded simultaneously. First, MILZC values are compared in general. Then average brain connections are used to quantify the effectiveness of acupuncture under the above four frequencies. Finally, significance index P values are used to study the spatiality of the acupuncture effect on the brain. Three main findings are obtained: (i) MILZC values increase during the acupuncture; (ii) manual acupunctures (MAs) with 100 times/rain and 150 times/min are more effective than with 50 times/min and 200 times/rain; (iii) contralateral hemisphere activation is more prominent than ipsilateral hemisphere's. All these findings suggest that acupuncture contributes to the increase of brain information exchange complexity and the MILZC method can successfully describe these changes.展开更多
Berger's "window on the mind" [1] has, with modem computing power, become a possibility. A portable electroencephalograph was used to demonstrate a correlation of personality with brain waves. In principle, this co...Berger's "window on the mind" [1] has, with modem computing power, become a possibility. A portable electroencephalograph was used to demonstrate a correlation of personality with brain waves. In principle, this could make it as useful a clinical tool for psychiatrists as the stethoscope is for physicians. Besides clinical use, the method could be a cheap, efficient way of investigating the effects ofpsychopharmaceutical drugs.展开更多
<strong>Background:</strong><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> The epileptic encephalo...<strong>Background:</strong><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> The epileptic encephalopathies collectively</span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">exact an immense personal, medical, and financial toll on</span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">the affected children, their families, and</span></span></span><span><span><span style="font-family:""> </span></span></span><span><span><span style="font-family:""><span style="font-family:Verdana;">the healthcare system.</span><b><span style="font-family:Verdana;"> Objective:</span></b><span style="font-family:Verdana;"> This study was aimed to delineate the clinical spectrum of patients with Epileptic encephalopathies (EEs) and classify them under various epileptic syndromes. </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> This was a cross-sectional study that was carried out in the department of Neurophysiology of the National Institute of Neurosciences and Hospital, Bangladesh from July 2016 to June 2019.</span></span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">Children with recurrent seizures which w</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">ere </span></span></span><span><span><span style="font-family:""><span style="font-family:Verdana;">difficult to control and associated with developmental arrest or regression in absence of a progressive brain pathology were considered to be suffering from EE. Children under 12 years of age fulfilling the inclusion criteria were enrolled in the study. These patients were evaluated clinically and Electroencephalography (EEG) was done in all children at presentation. Based on the clinical profile and EEG findings the patients were categorized under various epileptic syndromes according to International League Against Epilepsy (ILAE) classification 2010.</span><b><span style="font-family:Verdana;"> Results:</span></b><span style="font-family:Verdana;"> A total of 1256 children under 12 years of age were referred to the Neurophysiology Department. Among them, 162</span></span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">(12.90%) fulfilled the inclusion criteria. Most of the patients were male (64.2%) and below 1 year (37.7%) of age. The majority (56.8%) were delivered at the hospital and 40.1% had a history of perinatal asphyxia. Development was age-appropriate before the onset of a seizure in 38.9% of cases. Most (53.7%) of the patients had seizure onset within 3 months of age. Categorization of Epileptic syndromes found that majority had West Syndrome (WS)</span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">(37.65%) followed by Lennox-Gastaut syndrome (LGS) (22.22%), Otahara syndrome (11.73%), Continuous spike-and-wave during sleep (CSWS) (5.66%), Myoclonic astatic epilepsy (MAE)</span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">(4.94%), Early myoclonic encephalopathy (EME) (3.7%), Dravet</span></span></span><span><span><span style="font-family:""> </span></span></span><span><span><span style="font-family:""><span style="font-family:Verdana;">syndrome (3.7%) and Landau-Kleffner syndrome (LKS) (1.23%). 9.26% of syndromes were unclassified. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> EEG was found to be a useful tool in the evaluation of Epileptic encephalopathies. The clinico-electroencephalographic features are age-related. Their recognition and appropriate management are critical.</span></span></span></span>展开更多
Machine learning(ML)is a fundamental concept in the field of state-of-the-art artificial intelligence(AI).Over the past two decades,it has evolved rapidly and been employed wildly in many fields.In medicine the widesp...Machine learning(ML)is a fundamental concept in the field of state-of-the-art artificial intelligence(AI).Over the past two decades,it has evolved rapidly and been employed wildly in many fields.In medicine the widespread usage of ML has been observed in recent years.The present review examines various ML approaches for electroencephalograph(EEG)signal procession in epilepsy research,highlighting applications in the aspect of automated seizure detection,prediction and orientation.The present review also presents advantage,challenge and future direction of ML techniques in the analysis of EEG signals in epilepsy.展开更多
目的研究视觉对人体姿势控制影响及其脑功能网络连接机制。方法以15名健康青年为研究对象,要求受试者分别进行30 s睁眼、闭眼的双腿站立平衡,采集平衡过程中身体压力中心(center of pressure,COP)和脑电。对COP进行样本熵(SampleEn)计算...目的研究视觉对人体姿势控制影响及其脑功能网络连接机制。方法以15名健康青年为研究对象,要求受试者分别进行30 s睁眼、闭眼的双腿站立平衡,采集平衡过程中身体压力中心(center of pressure,COP)和脑电。对COP进行样本熵(SampleEn)计算;对脑电θ、α和β频段,计算相位滞后指数(phase lag index,PLI)构建大脑功能网络,并基于图论计算集聚系数(C)、特征路径长度(L)及小世界网络属性(σ)。结果人体在双腿站立平衡过程中,闭眼COPY样本熵显著高于睁眼(P<0.05)。闭眼α频段PLI平均值显著高于睁眼(P<0.05);闭眼α频段C、σ显著高于睁眼,L显著低于睁眼(P<0.05)。闭眼时α频段额区-中央区-顶区之间的网络连接以及中央区和顶区内连接强度显著高于睁眼(P<0.05)。闭眼时α频段PLI平均值以及C值与COPY样本熵中度呈中度负相关(P<0.05)。睁眼时左前额区、左顶区、左枕区α频段PLI平均值与COPY样本熵呈中度负相关;闭眼时左中央区、右枕区α频段PLI平均值则与COPY样本熵呈中度负相关。结论人体在站立平衡时,当没有视觉信息输入时,身体平衡稳定性下降,同时伴随着脑电α频段的脑网络连接增强以及大脑处理信息的效率需提升。人体在不同的视觉条件下进行姿势控制时,大脑会采用不同的神经策略。展开更多
Over the past several decades, numerous methods have been applied by research and professionals to detect and measure mental stress, varying from subjective methods such questionnaires and face-to-face interviews up t...Over the past several decades, numerous methods have been applied by research and professionals to detect and measure mental stress, varying from subjective methods such questionnaires and face-to-face interviews up to the objective methods using physiological signals and neuroimaging equipment such as salivary cortisol and functional magnetic resonance imaging (fMRI), respectively. Among those methods, an Electroencephalograph (EEG) is one of the utmost chosen non-invasive methods by professionals and researchers in recording real time brain signals. This paper highlights the state of art for each of the studies, by comparing and analyzing the method and protocol of EEG data collection, including the selection of electrodes and brain regions involving two major categories of mental stress: acute and chronic. Selection of EEG features, with the necessary signal pre-processing and processing techniques, and the classification models used in these studies have been summarized and discussed.展开更多
为探索神经反馈训练在提升射击表现方面的应用效果和训练过程中的无应答者特性,开展一项用于提升射击表现的神经反馈训练(neurofeedback training for sport performance,SP-NFT)实验研究,招募20名受试者,进行2周4次的“巅峰”范式SP-N...为探索神经反馈训练在提升射击表现方面的应用效果和训练过程中的无应答者特性,开展一项用于提升射击表现的神经反馈训练(neurofeedback training for sport performance,SP-NFT)实验研究,招募20名受试者,进行2周4次的“巅峰”范式SP-NFT,采集受试者前、后测隐显目标射击表现和相关脑电(electroencephalograph,EEG)数据,检验SP-NFT对射击表现的提升效果、静息态EEG特征、SP-NFT期间正常组和无应答组EEG特性变化情况。结果表明:受试者后测射击成绩显著高于前测(P<0.01),静息态theta频带功率显著降低(P<0.01);相对正常受试者,无应答者在SP-NFT期间的努力程度更高,theta频段功率和SMR功率的变化程度更低,SP-NFT能够有效提升受试者射击表现,进一步揭示了无应答者的相关生理机制。研究成果为用于提升射击表现的SP-NFT技术进一步发展提供理论支撑和实验证据。展开更多
目的观察利培酮与脑电生物反馈治疗对精神分裂症患者临床症状评分与社会功能的影响。方法选取2020年3月至2022年8月江西省精神病院90例精神分裂症患者作为研究对象,根据随机数字表法分为观察组与对照组,各45例。观察组接受利培酮联合脑...目的观察利培酮与脑电生物反馈治疗对精神分裂症患者临床症状评分与社会功能的影响。方法选取2020年3月至2022年8月江西省精神病院90例精神分裂症患者作为研究对象,根据随机数字表法分为观察组与对照组,各45例。观察组接受利培酮联合脑电生物反馈治疗,对照组仅采用利培酮治疗。比较两组临床症状[简明精神病量表(brief psychiatric rating scale,BPRS)评分]、认知功能[简易智能精神状态检查量表(mini-mental state examination,MMSE)]、日常行为能力[日常生活活动能力量表(activity of daily living,ADL)]、社会功能[住院精神患者社会功能评定量表(scale of social function in psychosis inpatients,SSPI)评分]。结果治疗后,观察组焦虑忧郁、缺乏活力、思维障碍、激活性、敌对猜疑评分均低于对照组,差异有统计学意义(P<0.05)。治疗后,观察组MMSE、ADL、SSPI评分均高于对照组,差异有统计学意义(P<0.05)。结论利培酮联合脑电生物反馈治疗精神分裂症效果良好,有助于改善患者临床症状,提高认知能力、日常行为能力与社会能力,值得临床推广应用。展开更多
基金Project supported by the Key Program of the National Natural Science Foundation of China (Grant No. 50537030)the National Natural Science Foundation of China (Grant Nos. 61072012 and 61172009)+1 种基金the Young Scientists Fund of the National Natural Science Foundation of China (Grant Nos. 61104032 and 60901035)the Tianjin Municipal Natural Science Foundation,China (Grant No. 12JCZDJC21100)
文摘Manual acupuncture is widely used for pain relief and stress control.Previous studies on acupuncture have shown its modulatory effects on the functional connectivity associated with one or a few preselected brain regions.To investigate how manual acupuncture modulates the organization of functional networks at a whole-brain level,we acupuncture at ST36 of a right leg to obtain electroencephalograph(EEG) signals.By coherence estimation,we determine the synchronizations between all pairwise combinations of EEG channels in three acupuncture states.The resulting synchronization matrices are converted into functional networks by applying a threshold,and the clustering coefficients and path lengths are computed as a function of threshold.The results show that acupuncture can increase functional connections and synchronizations between different brain areas.For a wide range of thresholds,the clustering coefficient during acupuncture and postacupuncture period is higher than that during the pre-acupuncture control period,whereas the characteristic path length is shorter.We provide further support for the presence of "small-world" network characteristics in functional networks by using acupuncture.These preliminary results highlight the beneficial modulations of functional connectivity by manual acupuncture,which could contribute to the understanding of the effects of acupuncture on the entire brain,as well as the neurophysiological mechanisms underlying acupuncture.Moreover,the proposed method may be a useful approach to the further investigation of the complexity of patterns of interrelations between EEG channels.
基金Project supported by the Key Program of the National Natural Science Foundation of China (Grant No. 50537030)the National Natural Science Foundation of China (Grant Nos. 61072012 and 61172009)+1 种基金the Young Scientists Fund of the National Natural Science Foundation of China (Grant Nos. 61104032 and 60901035)the Tianjin Municipal Natural Science Foundation (Grant No. 12JCZDJC21100)
文摘To investigate whether and how manual acupuncture(MA) modulates brain activities,we design an experiment where acupuncture at acupoint ST36 of the right leg is used to obtain electroencephalograph(EEG) signals in healthy subjects.We adopt the autoregressive(AR) Burg method to estimate the power spectrum of EEG signals and analyze the relative powers in delta(0 Hz-4 Hz),theta(4 Hz-8 Hz),alpha(8 Hz-13 Hz),and beta(13 Hz-30 Hz) bands.Our results show that MA at ST36 can significantly increase the EEG slow wave relative power(delta band) and reduce the fast wave relative powers(alpha and beta bands),while there are no statistical differences in theta band relative power between different acupuncture states.In order to quantify the ratio of slow to fast wave EEG activity,we compute the power ratio index.It is found that the MA can significantly increase the power ratio index,especially in frontal and central lobes.All the results highlight the modulation of brain activities with MA and may provide potential help for the clinical use of acupuncture.The proposed quantitative method of acupuncture signals may be further used to make MA more standardized.
基金supported by the Key Program of the National Natural Science Foundation of China (Grant No.50537030)the National Natural Science Foundation of China (Grant No.61072012)the Young Scientists Fund of the National Natural Science Foundation of China (Grant Nos.50907044,61104032,and 60901035)
文摘As a convenient approach to the characterization of cerebral cortex electrical information, electroencephalograph (EEG) has potential clinical application in monitoring the acupuncture effects. In this paper, a method composed of the mutual information method and Lempel-Ziv complexity method (MILZC) is proposed to investigate the effects of acupuncture on the complexity of information exchanges between different brain regions based on EEGs. In the experiments, eight subjects are manually acupunctured at 'Zusanli' acupuncture point (ST-36) with different frequencies (i.e., 50, 100, 150, and 200 times/min) and the EEGs are recorded simultaneously. First, MILZC values are compared in general. Then average brain connections are used to quantify the effectiveness of acupuncture under the above four frequencies. Finally, significance index P values are used to study the spatiality of the acupuncture effect on the brain. Three main findings are obtained: (i) MILZC values increase during the acupuncture; (ii) manual acupunctures (MAs) with 100 times/rain and 150 times/min are more effective than with 50 times/min and 200 times/rain; (iii) contralateral hemisphere activation is more prominent than ipsilateral hemisphere's. All these findings suggest that acupuncture contributes to the increase of brain information exchange complexity and the MILZC method can successfully describe these changes.
文摘Berger's "window on the mind" [1] has, with modem computing power, become a possibility. A portable electroencephalograph was used to demonstrate a correlation of personality with brain waves. In principle, this could make it as useful a clinical tool for psychiatrists as the stethoscope is for physicians. Besides clinical use, the method could be a cheap, efficient way of investigating the effects ofpsychopharmaceutical drugs.
文摘<strong>Background:</strong><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> The epileptic encephalopathies collectively</span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">exact an immense personal, medical, and financial toll on</span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">the affected children, their families, and</span></span></span><span><span><span style="font-family:""> </span></span></span><span><span><span style="font-family:""><span style="font-family:Verdana;">the healthcare system.</span><b><span style="font-family:Verdana;"> Objective:</span></b><span style="font-family:Verdana;"> This study was aimed to delineate the clinical spectrum of patients with Epileptic encephalopathies (EEs) and classify them under various epileptic syndromes. </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> This was a cross-sectional study that was carried out in the department of Neurophysiology of the National Institute of Neurosciences and Hospital, Bangladesh from July 2016 to June 2019.</span></span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">Children with recurrent seizures which w</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">ere </span></span></span><span><span><span style="font-family:""><span style="font-family:Verdana;">difficult to control and associated with developmental arrest or regression in absence of a progressive brain pathology were considered to be suffering from EE. Children under 12 years of age fulfilling the inclusion criteria were enrolled in the study. These patients were evaluated clinically and Electroencephalography (EEG) was done in all children at presentation. Based on the clinical profile and EEG findings the patients were categorized under various epileptic syndromes according to International League Against Epilepsy (ILAE) classification 2010.</span><b><span style="font-family:Verdana;"> Results:</span></b><span style="font-family:Verdana;"> A total of 1256 children under 12 years of age were referred to the Neurophysiology Department. Among them, 162</span></span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">(12.90%) fulfilled the inclusion criteria. Most of the patients were male (64.2%) and below 1 year (37.7%) of age. The majority (56.8%) were delivered at the hospital and 40.1% had a history of perinatal asphyxia. Development was age-appropriate before the onset of a seizure in 38.9% of cases. Most (53.7%) of the patients had seizure onset within 3 months of age. Categorization of Epileptic syndromes found that majority had West Syndrome (WS)</span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">(37.65%) followed by Lennox-Gastaut syndrome (LGS) (22.22%), Otahara syndrome (11.73%), Continuous spike-and-wave during sleep (CSWS) (5.66%), Myoclonic astatic epilepsy (MAE)</span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">(4.94%), Early myoclonic encephalopathy (EME) (3.7%), Dravet</span></span></span><span><span><span style="font-family:""> </span></span></span><span><span><span style="font-family:""><span style="font-family:Verdana;">syndrome (3.7%) and Landau-Kleffner syndrome (LKS) (1.23%). 9.26% of syndromes were unclassified. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> EEG was found to be a useful tool in the evaluation of Epileptic encephalopathies. The clinico-electroencephalographic features are age-related. Their recognition and appropriate management are critical.</span></span></span></span>
基金the National Natural Science Foundation of China(NSFC)(NO.81701269).
文摘Machine learning(ML)is a fundamental concept in the field of state-of-the-art artificial intelligence(AI).Over the past two decades,it has evolved rapidly and been employed wildly in many fields.In medicine the widespread usage of ML has been observed in recent years.The present review examines various ML approaches for electroencephalograph(EEG)signal procession in epilepsy research,highlighting applications in the aspect of automated seizure detection,prediction and orientation.The present review also presents advantage,challenge and future direction of ML techniques in the analysis of EEG signals in epilepsy.
文摘目的研究视觉对人体姿势控制影响及其脑功能网络连接机制。方法以15名健康青年为研究对象,要求受试者分别进行30 s睁眼、闭眼的双腿站立平衡,采集平衡过程中身体压力中心(center of pressure,COP)和脑电。对COP进行样本熵(SampleEn)计算;对脑电θ、α和β频段,计算相位滞后指数(phase lag index,PLI)构建大脑功能网络,并基于图论计算集聚系数(C)、特征路径长度(L)及小世界网络属性(σ)。结果人体在双腿站立平衡过程中,闭眼COPY样本熵显著高于睁眼(P<0.05)。闭眼α频段PLI平均值显著高于睁眼(P<0.05);闭眼α频段C、σ显著高于睁眼,L显著低于睁眼(P<0.05)。闭眼时α频段额区-中央区-顶区之间的网络连接以及中央区和顶区内连接强度显著高于睁眼(P<0.05)。闭眼时α频段PLI平均值以及C值与COPY样本熵中度呈中度负相关(P<0.05)。睁眼时左前额区、左顶区、左枕区α频段PLI平均值与COPY样本熵呈中度负相关;闭眼时左中央区、右枕区α频段PLI平均值则与COPY样本熵呈中度负相关。结论人体在站立平衡时,当没有视觉信息输入时,身体平衡稳定性下降,同时伴随着脑电α频段的脑网络连接增强以及大脑处理信息的效率需提升。人体在不同的视觉条件下进行姿势控制时,大脑会采用不同的神经策略。
文摘Over the past several decades, numerous methods have been applied by research and professionals to detect and measure mental stress, varying from subjective methods such questionnaires and face-to-face interviews up to the objective methods using physiological signals and neuroimaging equipment such as salivary cortisol and functional magnetic resonance imaging (fMRI), respectively. Among those methods, an Electroencephalograph (EEG) is one of the utmost chosen non-invasive methods by professionals and researchers in recording real time brain signals. This paper highlights the state of art for each of the studies, by comparing and analyzing the method and protocol of EEG data collection, including the selection of electrodes and brain regions involving two major categories of mental stress: acute and chronic. Selection of EEG features, with the necessary signal pre-processing and processing techniques, and the classification models used in these studies have been summarized and discussed.
文摘为探索神经反馈训练在提升射击表现方面的应用效果和训练过程中的无应答者特性,开展一项用于提升射击表现的神经反馈训练(neurofeedback training for sport performance,SP-NFT)实验研究,招募20名受试者,进行2周4次的“巅峰”范式SP-NFT,采集受试者前、后测隐显目标射击表现和相关脑电(electroencephalograph,EEG)数据,检验SP-NFT对射击表现的提升效果、静息态EEG特征、SP-NFT期间正常组和无应答组EEG特性变化情况。结果表明:受试者后测射击成绩显著高于前测(P<0.01),静息态theta频带功率显著降低(P<0.01);相对正常受试者,无应答者在SP-NFT期间的努力程度更高,theta频段功率和SMR功率的变化程度更低,SP-NFT能够有效提升受试者射击表现,进一步揭示了无应答者的相关生理机制。研究成果为用于提升射击表现的SP-NFT技术进一步发展提供理论支撑和实验证据。
文摘目的观察利培酮与脑电生物反馈治疗对精神分裂症患者临床症状评分与社会功能的影响。方法选取2020年3月至2022年8月江西省精神病院90例精神分裂症患者作为研究对象,根据随机数字表法分为观察组与对照组,各45例。观察组接受利培酮联合脑电生物反馈治疗,对照组仅采用利培酮治疗。比较两组临床症状[简明精神病量表(brief psychiatric rating scale,BPRS)评分]、认知功能[简易智能精神状态检查量表(mini-mental state examination,MMSE)]、日常行为能力[日常生活活动能力量表(activity of daily living,ADL)]、社会功能[住院精神患者社会功能评定量表(scale of social function in psychosis inpatients,SSPI)评分]。结果治疗后,观察组焦虑忧郁、缺乏活力、思维障碍、激活性、敌对猜疑评分均低于对照组,差异有统计学意义(P<0.05)。治疗后,观察组MMSE、ADL、SSPI评分均高于对照组,差异有统计学意义(P<0.05)。结论利培酮联合脑电生物反馈治疗精神分裂症效果良好,有助于改善患者临床症状,提高认知能力、日常行为能力与社会能力,值得临床推广应用。