目的观察理筋正骨手法结合肌内效贴治疗急性期肩关节周围炎的临床疗效。方法选择60例急性期肩关节周围炎患者,随机分为手法组和对照组,每组30例。手法组给予理筋正骨手法结合肌内效贴治疗,对照组给予超短波疗法结合肌内效贴治疗。比较...目的观察理筋正骨手法结合肌内效贴治疗急性期肩关节周围炎的临床疗效。方法选择60例急性期肩关节周围炎患者,随机分为手法组和对照组,每组30例。手法组给予理筋正骨手法结合肌内效贴治疗,对照组给予超短波疗法结合肌内效贴治疗。比较两组患者临床疗效及治疗前后视觉模拟量表(visual analog scale,VAS)评分、压痛阈值、肩关节活动度(range of motion,ROM)、肩关节功能Constant-Murley评分(Constant-Murley score,CMS)、表面肌电积分肌电图(integral electromyogram,iEMG)值。结果手法组疗效优于对照组(P<0.05);两组治疗后VAS评分均显著降低,且手法组降低程度大于对照组(P<0.05);两组治疗后压痛阈值、CMS、肩关节ROM、iEMG值均显著升高(P<0.05),且手法组升高程度大于对照组(P<0.05)。结论理筋正骨手法结合肌内效贴治疗可缓解急性期肩关节周围炎患者的疼痛,改善肩关节功能。展开更多
Objective To observe the therapeutic effect of sinew-regulating bone-setting manipulations for knee osteoarthritis(KOA)model rabbits and its impacts on the chondrocyte apoptosis rate and the levels of interleukin(IL)-...Objective To observe the therapeutic effect of sinew-regulating bone-setting manipulations for knee osteoarthritis(KOA)model rabbits and its impacts on the chondrocyte apoptosis rate and the levels of interleukin(IL)-1βand nitric oxide(NO).Methods According to the random number table method,30 New Zealand white rabbits were divided into a normal group(n=9)and a modeling group(n=21).Rabbits in the modeling group were used to establish KOA models with the modified Hulth method.At the 8th week,three rabbits were sacrificed to verify the model and the remaining 18 rabbits were randomly divided into a model group(n=9)and an intervention group(n=9).Rabbits in the normal group and model group were bred routinely without any intervention.Rabbits in the intervention group were treated with the sinew-regulating bone-setting manipulations,10 min/time,once every other day for a total of 20 times.The Lequesne MG knee function rating was used to evaluate the behavioral differences of the rabbits in each group.The Pelletier score was used to evaluate the general changes of the rabbits.The Mankin score was used to evaluate the pathology of knee cartilages.The enzyme-linked immunosorbent assay and nitrate reductase methods were used to determine the levels of IL-1βand NO in serum and synovial fluid of each group,respectively.In situ terminal deoxynucleotidyl transferase-mediated nick and labeling method was used to determine the apoptosis of chondrocytes in each group.Results Compared with the normal group,the scores of Lequesne MG,Pelletier and Mankin,and the levels of IL-1βand NO in the model group were increased(P<0.05),which indirectly indicated the success of the model.Compared with the model group,the scores of Lequesne MG,Pelletier and Mankin,IL-1βand NO levels,and chondrocyte apoptosis rate of the intervention group were decreased,and the differences were statistically significant(P<0.05).Conclusion The sinew-regulating bone-setting manipulations can reduce the levels of IL-1β,NO,and chondrocyte apoptosis rate,and delay the articular cartilage degeneration,therefore,having a good therapeutic effect on KOA.展开更多
文摘目的观察理筋正骨手法结合肌内效贴治疗急性期肩关节周围炎的临床疗效。方法选择60例急性期肩关节周围炎患者,随机分为手法组和对照组,每组30例。手法组给予理筋正骨手法结合肌内效贴治疗,对照组给予超短波疗法结合肌内效贴治疗。比较两组患者临床疗效及治疗前后视觉模拟量表(visual analog scale,VAS)评分、压痛阈值、肩关节活动度(range of motion,ROM)、肩关节功能Constant-Murley评分(Constant-Murley score,CMS)、表面肌电积分肌电图(integral electromyogram,iEMG)值。结果手法组疗效优于对照组(P<0.05);两组治疗后VAS评分均显著降低,且手法组降低程度大于对照组(P<0.05);两组治疗后压痛阈值、CMS、肩关节ROM、iEMG值均显著升高(P<0.05),且手法组升高程度大于对照组(P<0.05)。结论理筋正骨手法结合肌内效贴治疗可缓解急性期肩关节周围炎患者的疼痛,改善肩关节功能。
文摘Objective To observe the therapeutic effect of sinew-regulating bone-setting manipulations for knee osteoarthritis(KOA)model rabbits and its impacts on the chondrocyte apoptosis rate and the levels of interleukin(IL)-1βand nitric oxide(NO).Methods According to the random number table method,30 New Zealand white rabbits were divided into a normal group(n=9)and a modeling group(n=21).Rabbits in the modeling group were used to establish KOA models with the modified Hulth method.At the 8th week,three rabbits were sacrificed to verify the model and the remaining 18 rabbits were randomly divided into a model group(n=9)and an intervention group(n=9).Rabbits in the normal group and model group were bred routinely without any intervention.Rabbits in the intervention group were treated with the sinew-regulating bone-setting manipulations,10 min/time,once every other day for a total of 20 times.The Lequesne MG knee function rating was used to evaluate the behavioral differences of the rabbits in each group.The Pelletier score was used to evaluate the general changes of the rabbits.The Mankin score was used to evaluate the pathology of knee cartilages.The enzyme-linked immunosorbent assay and nitrate reductase methods were used to determine the levels of IL-1βand NO in serum and synovial fluid of each group,respectively.In situ terminal deoxynucleotidyl transferase-mediated nick and labeling method was used to determine the apoptosis of chondrocytes in each group.Results Compared with the normal group,the scores of Lequesne MG,Pelletier and Mankin,and the levels of IL-1βand NO in the model group were increased(P<0.05),which indirectly indicated the success of the model.Compared with the model group,the scores of Lequesne MG,Pelletier and Mankin,IL-1βand NO levels,and chondrocyte apoptosis rate of the intervention group were decreased,and the differences were statistically significant(P<0.05).Conclusion The sinew-regulating bone-setting manipulations can reduce the levels of IL-1β,NO,and chondrocyte apoptosis rate,and delay the articular cartilage degeneration,therefore,having a good therapeutic effect on KOA.
