摘要
烧冲复合伤是平战时常见的致命性损伤,它较单纯的烧伤或冲击伤更严重,其救治困难,病死率高。临床资料表明,肺是烧冲复合伤最易受损的脏器,也是影响烧冲复合伤患者预后的重要因素,因此,肺损伤的治疗是治疗烧伤复合伤的关键。肺泡Ⅱ型上皮细胞(AECⅡ)损伤在肺损伤中起重要的作用。近年来有关烧冲复合伤时AECⅡ损伤的机制及干预措施的研究逐渐成为外科领域的研究热点之一,本文现就有关烧冲复合伤时AECⅡ损伤的机制及干预措施的研究综述如下。
Burn-blast combined injury is common traumatic injury in both wars and daily life .It′s more serious than burn or blast injury , the treatment of burn-blast combined injury is more difficult , and it’ s mortality is higher .Clinical data has shown that lung is the main target organ in the burn-blast combined injury.The degree of lung injury is closely related to the prognosis of patients with burn-blast combined injury.So the treatment of lung injury is the key factor for the treatment of burn-blast combined injury .Pre-clinical research has shown that the alveolar type Ⅱepithelial cell ( AECⅡ) plays an important role in the development of the occurrence of lung injury during burn-blast combined injury .In recent years , the mechanism and and treatment of injured AEC Ⅱ in burn-blast combined injury has become one of the hotspots in the field of surgery .In this review, the mechanisms and treatment of injured ACE Ⅱ in burn-blast combined injury are discussed .
出处
《中华损伤与修复杂志（电子版）》
CAS
2016年第6期-,共4页
Chinese Journal of Injury Repair and Wound Healing(Electronic Edition)
基金
全军"十二五"后勤科研计划课题资助项目(CKJ12J027)
哈尔滨市科技局科技创新人才研究专项资金项目(2016RAQXJ159
2015RAQYJ078)
关键词
烧冲复合伤
肺泡
上皮细胞
肺损伤
Burn-blast combined injury
Pulmonary alveoli
Epithelial cells
Lung injury
