摘要
肾纤维化是指肾脏在各种原发或继发因素下导致其功能损伤、结构改变,逐渐出现肾小球、血管及间质纤维基质沉积增加,最终导致慢性肾脏病(chronic kidney disease, CKD)及终末肾衰竭。为了给纤维化诊治提供新的理论依据,作者就肾纤维化信号通路及其最新致病机制进行综述。
Renal fibrosis refers to the kidney in a variety of primary or secondary factors leading to functional damage, structural changes, the gradual increase in glomerular, vascular and interstitial deposition of fibrous matrix, the result is chronic kidney disease (CKD) and end-stage chronic kidney disease failure. In order to provide a new theoretical basis for the diagnosis and treatment of renal fibrosis, the author reviews the signal pathway of renal fibrosis and its latest pathogenesis.
出处
《临床医学进展》
2022年第11期10870-10877,共8页
Advances in Clinical Medicine
