摘要
目的:观察益肾蠲痹丸内服配合双柏散外敷治疗急性痛风性关节炎的疗效。方法:72例急性痛风性关节炎患者随机分为两组:治疗组36例,对照组36例。治疗组给予益肾蠲痹丸内服(1次10 g,每日3次)和双柏散外敷(黄酒调成膏状,外敷于患处,厚度约0.5 cm,纱布包裹后用绷带固定,每12 h更换1次)治疗,对照组给予秋水仙碱片(1次2片,0.5mg/片,每日3次)和对乙酰氨基酚片(1次1片,300 mg/片,每日3次)治疗。观察比较两组治疗效果。结果:两组患者治疗后,治疗组总有效率为94.44%,对照组总有效率为77.78%。相比于对照组,治疗组的关节疼痛、关节急性红肿、关节压痛及关节活动受限的症状积分分别降低了38.41%、37.06%、42.86%、40.15%,P<0.05。血尿酸和血沉水平分别降低了20.77%、38.98%,P<0.05。复发率降低为对照组的16.67%。结论:益肾蠲痹丸内服配合双柏散外敷治疗急性痛风性关节炎有较显著疗效。
Objective: To observe the effect of Yishenjuanbi Pill orally taken plus Shuangbo Powder external application in the treatment of acute gouty arthritis.Method: Seventy-two patients were randomly divided into treatment group and control group,while thirty-six patients in each group.Treatment group received Yishen Juanbi wan orally taken(10 g each time,3 times daily) and Shuangbo Powder external application(paste made from yellow rice wine appllied in the affected area with the thickness about 0.5cm,and fixed with gauze bandage,change once every 12 h),the control group received colchicine tablets(2 tablets each time,0.5mg/each tablet,3 times daily) and paracetamol tablets(1 tablet each time,300mg/each tablet,3 times daily).Compare the therapeutic effect of two groups.Result: The treatment group's effective rate was 94.44%,the control group's rate was 77.78%.Compared with the control group,the grade of arthralgia,acute inflamed joints joint tenderness and joint function were reduced 38.41%,37.06%,42.86% and 40.15%,respectively,P<0.05.Level of blood uric acid and blood sedimentation were reduced 20.77% and 38.98%,respectively,P<0.05.The recurrence rate was decreased to 16.67% in the control group.Conclusion: Yishenjuanbi Pill orally taken plus Shuangbo Powder external application shows significant efficacy in the treatment of acute gouty arthritis.
出处
《中药药理与临床》
CAS
CSCD
北大核心
2015年第2期94-96,共3页
Pharmacology and Clinics of Chinese Materia Medica
关键词
益肾蠲痹丸
双柏散
急性痛风性关节炎
临床观察
Yishenjuanbi Pill(益肾蠲痹丸)
Shuangbo Powder(双柏散)
acute gouty arthritis
clinical observation
