摘要
随着老龄化社会的到来,作为最常见的神经变性疾病之一,帕金森病(Parkinson’s disease,PD)的发病率、患病率、死亡率呈明显上升态势。正确认识PD,不断促进PD临床诊断准确性的提高,提高早期诊断率有助于积极应对这一挑战。本文拟结合作者所在学科及国内相关中心的近期工作就我国PD诊断和治疗现状进行一概述,对近年来在PD样本库建设及其发现,影像学及体液标志物研究,以及治疗和相关指南更新进行介绍,力图阐释近三年来中国PD诊疗的现况和进展。
Parkinson’s disease(PD)is one of the most common neurodegenerative diseases at present,and with the advent of aging society,there are significant increases in the incidence,prevalence,and mortality rates of this disease.A correct understanding of PD,continuous improvement of the accuracy of clinical diagnosis,and improvement in early diagnostic rate may help to actively cope with this challenge.With reference to the recent studies in related centers in China,this article reviews the current status of the diagnosis and treatment of PD and introduces the establishment of PD Biobank,the research on imaging and humoral markers,and the updates in treatment and related guidelines,in order to explain the current status of PD diagnosis and treatment as well as research advances in China over the past three years.
作者
王刚
崔海伦
Wang Gang;Cui Hailun(Department of Neurology&Neuroscience Institute,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine)
出处
《重庆医科大学学报》
CAS
CSCD
北大核心
2019年第4期464-467,共4页
Journal of Chongqing Medical University
关键词
帕金森病
诊断
治疗
Parkinson’s disease
diagnosis
treatment