摘要
目的探究妊娠晚期孕妇B族链球菌带菌检测情况及B族链球菌带菌对妊娠结局的影响。方法选取2016年6月-2017年3月于医院进行产前检查并待产的500例妊娠晚期孕妇为研究对象,取孕妇肛周分泌物及阴道下三分之一分泌物实施B族链球菌检测,分析孕妇B族链球菌带菌情况与B族链球菌带菌对妊娠结局及新生儿的影响。结果 500例妊娠晚期孕妇B族链球菌阳性率为9.40%(47/500);B族链球菌阳性孕妇妊娠结局中宫内窘迫、宫内感染发生率分别为44.68%(21/47)、17.02%(8/47)高于B族链球菌阴性孕妇(P<0.05)。B族链球菌阳性孕妇中新生儿B族链球菌阳性与上呼吸道感染及肺炎发生率分别为23.40%(11/47)与19.15%(9/47)及21.28%(10/47)高于B族链球菌阴性孕妇新生儿(P<0.001)。结论妊娠晚期孕妇B族链球菌感染会导致胎儿窘迫、宫内感染及新生儿感染发生率的增加,影响妊娠结局以及新生儿健康,因而在孕期需要对孕妇进行B族链球菌筛查,进而改善预后。
OBJECTIVE To investigate the detection of group B Streptococcus in pregnant women in late pregnancy and the effect of group B Streptococcus infection on pregnancy outcome.METHODS A total of 500 pregnant women in late pregnancy who underwent prenatal examination in the hospital from Jun.2016 to Mar.2017 were selected as the study subjects.The perianal secretions and vaginal secretions of pregnant women were collected for detection of Group B Streptococcus.The infection of group B Streptococcus in pregnant women and the effect of group B Streptococcus on pregnancy outcome and newborn were analyzed.RESULTS The positive rate of group B Streptococcus in late pregnancy was 9.40%in the 500 pregnant women(47/500).The incidences of intrauterine distress and intrauterine infection in pregnancy outcomes of group B Streptococcus positive pregnant women were44.68%(21/47)and 17.02%(8/47)significantly higher than those of group B Streptococcus negative pregnant women(P<0.05).The group B Streptococcus positive rate,and the incidences of upper respiratory tract infection and pneumonia in newborns of group B Streptococcus positive pregnant women were 23.40%(11/47),19.15%(9/47)and 21.28%(10/47),which were significantly higher than those of the newborns of the Group B Streptococcus negative pregnant women(P<0.001).CONCLUSION Group B Streptococcus infection in late pregnancy can lead to fetal distress,intrauterine infection and increased incidence of neonatal infection,affecting the outcome of pregnancy and neonatal health.Therefore,group B Streptococcus screening should be carried out during pregnancy to improve the prognosis.
作者
冯莹
许成芳
饶燕珍
邓小兰
孙珂
FENG Ying;XU Cheng-fang;RAO Yan-zhen;DENG Xiao-lan;SUN Ke(The Third Affiliated Hospital of Sun Yat-Sen University,Guangzhou,Guangdong510630,China)
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2019年第3期440-442,447,共4页
Chinese Journal of Nosocomiology
基金
广州市产学研协同创新重大专项基金资助项目(2060404)
关键词
B族链球菌
妊娠结局
新生儿感染
妊娠晚期
Group B Streptococcus
Pregnancy outcome
Neonatal infection
Late pregnancy
