摘要
采用单克隆抗体间接免疫荧光法测定了34例反复呼吸道感染患儿(RRI)的T淋巴细胞亚群(CD_(3、4、8)),并与21例健康儿童对照。结果表明患儿组CD_4明显低于正常组(P<0.05)。随机选择18例RRI患儿,经用胸腺素、转移因子治疗后CD_4较治疗前显著性提高(P<0.05)。提示RRI患儿存在CD_4细胞亚群低下而导致细胞免疫功能异常,通过免疫调节剂治疗而使之改善。
T - lymphocyte subsets ( CD3,4,8 ) is determined in 34 children with RRI by McAb indirect immuaofluorescence and in comparison with 21 healthy children. It is showed that the numbers of CD4 cells in RRI children is lower than in controls ( P<0.05). The numbers of CD4 cells are significantly increased after being treated with thymosin and Transfer factor ( P<0.05) in 18 patients selected randomly. It suggests that the abnormality of the cellular immunological function is caused by lower number of CD4 cells and can be improved by immunotherapy in RRI children.
出处
《温州医学院学报》
CAS
1992年第4期193-195,共3页
Journal of Wenzhou Medical College
关键词
呼吸系统疾病
T细胞
儿童
respiratory tract infections
T-lymphocyte
immunofluore-scence
thymosin
Transfer factor
