摘要
目的了解轮状病毒活疫苗预防轮状病毒腹泻的安全性及有效性。方法采用面访与自填式相结合的问卷以及电话调查方法,选择2008年—2013年间在大同市新和医院定期接种疫苗的7个月龄~3周岁健康婴幼儿287人及未接种疫苗的对照组207人,分别按年龄分为3组进行观察。结果接种组72 h后发生体温反应的男女间无明显性别差异、年龄无明显差异,且疫苗引起的体温反应较小;发生消化道症状的有7例。对照组发生反应的人数较少,仅为3例;但8个月后,接种组腹泻患病率明显低于对照组。结论口服轮状病毒活疫苗是预防轮状病毒腹泻安全、有效的手段。
Objective To understand the safety and efficacy of rotavirus live vaccines in safety and efficacy at different age group after vaccination. Methods Combining face to face interviews and self administered questionnaires and telephone survey methods: 287 healthy infants inoculated and 207 cases infants in control group from 7 months old to 3 years of hospital in Datong xinhe were chose from 2008~2013. We divided three groups by age respectively. Results It didn't correlated with sex and age that had thermal reactions after 72 hours. Vaccine caused the temperature response was small. There were 7 cases in digestive tract symptom. Control group had minimal number reaction which had 3 peple. But group of inoculation with diarrhea disease was significantly lower than that of the control group after 8 months. Conclusion Oral rotavirus vaccine was safe and effective means of prevention of rotavirus diarrhea.
出处
《基层医学论坛》
2015年第S1期89-90,共2页
The Medical Forum
