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奥曲肽不同给药方式在胰腺炎患者中的应用及疗效对比观察 被引量:6

Observation on the application of octreotide in different forms on patients with pancreatitis and compared its curative effects
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摘要 目的:探讨奥曲肽不同给药方式在胰腺炎患者中的临床应用效果。方法:2010年5月-2013年6月收治胰腺炎患者60例,平均分成观察组和对照组,对照组给予皮下注射奥曲肽,观察组给予微量注射泵,观察两组患者临床效果。结果:观察组的治疗总有效率和对照组相比,差异具有统计学意义(P<0.05);观察组不良反应发生率和对照组相比,差异具有统计学意义(P<0.05);观察组各项指标(体征好转、血淀粉酶消退、住院时间)和对照组相比,差异具有统计学意义(P<0.05)。结论:奥曲肽治疗胰腺炎患者过程中借助微量注射泵给药方式,临床效果显著,值得推广使用。 Objective:To explore the clinical effect of octreotide in different ways application on patients with pancreatitis. Methods:60 patients with pancreatitis were selected from May 2010 to June 2013.They were divided into the observation group and the control group with 30 cases in each.The control group were given octreotide by subcutaneous injection,while the observation group were given octreotide with micro injection pump,then we observed the clinical results in patients of two groups. Results:The difference in the total efficiency had statistically significant between the observation group and the control group(P<0.05);the occurrence rate of adverse reactions also had clinical difference between the two groups,and the difference was statistically significant(P<0.05);in addation,compared with the control groups,each index(signs become better,blood amylase subsided,hospitalization time) in the observation group were better,and the differences were statistically significant(P<0.05). Conclusion:Given octreotide for patients with pancreatitis by micro injection pump has significantly clinical efficacy,so it is worth to be promote.
作者 莫有海
出处 《中国社区医师》 2015年第12期54-55,共2页 Chinese Community Doctors
关键词 奥曲肽 胰腺炎 临床效果 Octreotide Pancreatitis Clinical effect
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  • 1王艳蕾,贾玉杰,王立娜,姜妙娜,赵景霞.善宁对重症急性胰腺炎胰腺细胞的保护作用[J].四川大学学报(医学版),2005,36(1):134-135. 被引量:11
  • 2黄鹤光,陈燕昌,卢星榕,赵文新,许春森.不同剂量的奥曲肽对胰液分泌的影响[J].中华普通外科杂志,2006,21(3):226-226. 被引量:2
  • 3林瑛.善宁治疗重症胰腺炎的临床观察[J].医药世界,2006(9):55-56. 被引量:5
  • 4黄延年,陈思文,汤志威,曾宪成.乌司他丁与奥曲肽联合治疗急性胰腺炎的疗效观察[J].中国医院药学杂志,2006,26(11):1391-1393. 被引量:28
  • 5Chiang DT,Anozie A,Fleming WR,et al.Comparative study on actlte pancreatitis managoment[J].ANZ J Surg,2004,74:218221.
  • 6Niederau C,Schulz HU.Current Conservative Treatment of Acute Pancreatitis Evidence from Animal and Human studies.Hepato-Gastroenterol,1993,40:538-549.
  • 7Paran K,Heufeld D,Mayo A,et al.preliminary report of a prospectiver amdomized study of octreatide in the treatment of severe acute pancreatitis.J Am Coll Surg,1995,181(2):121-124.
  • 8Macfie J.Enteral versus parenteral nutrition:the singnificance of bacterial translocation and gut-barrier function[J].Nutrition,2000,16:606.
  • 9Wang X,Wang B,Wu J,et al.Beneficial effect of growt h hormomeon bacterial t ranslocation during t he course of acnte necrotizing[J].pancreatitis in rat s pancreas,2001,23:148156.
  • 10陈灏珠.实用内科学[M].北京:人民卫生出版社,2002.1843.

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