摘要
目的:探讨氨氯地平联合卡托普利治疗高血压合并冠心病患者的临床疗效。方法:2011年3月-2013年4月收治高血压合并冠心病患者80例,平均分成观察组和对照组,观察组给予氨氯地平联合卡托普利治疗,对照组给予临床常规治疗,比较两组患者临床疗效。结果:经相应治疗后,两组患者临床症状均发生明显性变化,观察组治疗好转率优于对照组(95.0%vs80.0%),差异有统计学意义(P<0.05);观察组头晕、恶心、腹泻等不良反应发生率低于对照组(12.5%vs25.0%),差异有统计学意义(P<0.05);观察组治疗后血压、心绞痛改善情况优于对照组,差异有统计学意义(P<0.05)。结论:氨氯地平联合卡托普利治疗高血压合并冠心病患者,临床效果显著,可提高临床治愈率,改善血压,值得推广使用。
Objective:To investigate the clinical effect of amlodipine combined with captopril in the treatment of patients with hypertension and coronary heart disease.Methods:80 patients with hypertension and coronary heart disease were selected from March 2011 to April 2013.They were divided into the observation group and the control group.Patients in the observation group were given amlodipine combined with captopril,while patients in the control group were treated with routine clinical treatment, then we compared the clinical efficacy in patients of two groups.Results:After treatment,the clinical symptoms were significantly changed in two groups,however,the the observation group improved obviously than the control group(95.0% vs80.0% ),and the difference was statistically significant(P＜0.05);the incidence of adverse reaction such as dizziness,nausea and diarrhea etc, occurrenced in the observation group was less than in the control group(12.5% vs25.0% ),and the difference was statistically significant(P＜0.05);after treatment,the improvement on blood pressure and angina of patients in the observation group was better than the control group,and the difference was statistically significant(P＜0.05).Conclusion:Amlodipine combined with captopril in the treatment of patients with hypertension and coronary heart disease can achevie significantly clinical efficacy, improve the clinical cure rate, and improve blood pressure,so it is worthy of promotion.
出处
《中国社区医师》
2015年第12期26-27,共2页
Chinese Community Doctors
关键词
氨氯地平
卡托普利
高血压
冠心病
Amlodipine
Captopril
Hypertension
Coronary heart disease
