摘要
目的 探讨广西壮、汉族妇女骨密度 (bonemineraldensity ,BMD)和绝经后壮、汉族妇女骨质疏松 (osteoporosis,OP)发生率是否存在差异性 ,为骨质疏松防治提供依据。方法 居住南宁 1 0年以上的健康绝经前妇女 1 79名 ,绝经后妇女 1 6 3名 ,记录其祖父母、外祖父母的民族 ,祖父母和外祖父母均为同一民族 (汉族或壮族 )者纳入本研究。同时记录受试者的年龄、初潮年龄、绝经年限 (绝经后妇女 )、孕次、产次。受试前 3个月内至少有 1次月经来潮者纳入绝经前妇女组 ;绝经 1年或以上者纳入绝经后妇女组。测量身高、体重 ,计算体重指数 (BMI)。用法国DMS公司的DEXA检测受试者腰椎 (L2 ～L4)正位、左髋部(股骨颈、Word s三角、大转子 )、左前臂 (超远端、远端 )的BMD ,并进行比较。结果 绝经前壮族妇女除股骨颈、前臂BMD略高于 (0 93%～ 1 4 4 % )或等于汉族妇女外 ,其余检测部位的BMD均低于汉族妇女 (0 92 %～ 5 92 % ) ,其中L2 ～L4的BMD分别较汉族妇女低 4 92 % (P =0 0 6 7)、5 2 6 % (P =0 0 5 4 )、5 92 % (P =0 0 37) ;相反 ,绝经后壮族妇女除L2 和前臂超远端的BMD略低于 (0 1 5 %～ 0 99% )汉族妇女外 ,其余部位的BMD均高于 (0 1 3%～ 2 79% )汉族妇女 ,虽然差异无统计学意义 (P >0 0
Objective To investigate the difference of bone mineral density(BMD) in Guangxi zhuang and han national women.Methods 342 healthy women who have resided in Nanning over 10 years and their grandparents and maternal gradparents were the same nationality zhuang or han were included in this study.173 women whose grandparents and maternal gradparents both were han nationality were included in han nationality group;the other 169 women whose grandparents and maternal gradparents both were zhuang nationality were included in zhuang nationality group.A clinic questionaire was administered to record their age,age at menarche,years since natural menopause(for postmenopausal women),number or prior pregnancy and parturition.179 women who had experienced menstruation in the 3 months before screening were included in the premenopausal group;163 women who hadnt menstruated for 1 year or more were included in the postmenopausal group.Their height,weight and BMI were determined.Their BMD were examined at vertebrea(L 2～L 4),hip and radius by DEXA.Results In premenopausal group,except for the femoral neck and radius BMD was a little more higher(0 93%～1 44%) or equal in Zhuang women than in han women,but at other examined sites,the BMD was higher in han than in Zhuang women(0 92%～5 92%,expecially the L 2～L 4 BMD was 4 92%,5 26% and 5 92% higher(P=0 067,0 054 and 0 037,respectively) in han than in zhuang women.To the contrary,in postmenopausal group,except for the L 2 and ultradistal BMD was a little more higher(0 15%～0 99%) in han than in zhuang women,at other sites,the BMD was higher(0 13%～2 79%) in zhuang than in han women,but there was no significant differences in BMD between han and zhuang postmenopausal women(P>0 05).The rates of osteoporosis in han and zhuang postmenopausal women were 30 2% and 35 1%,respectively,and there was no significant difference between them.Conclusion The national difference in BMD between han and zhuang women may appear probably at vertebrea only in premenopausal women,the rate of bone loss may speeder in han than in zhuang postmenopausal women;the rate of osteoporosis between han and zhuang postmenopausal women was no significant difference.
出处
《广西医学》
CAS
2004年第1期16-19,共4页
Guangxi Medical Journal
