促肾上腺皮质激素释放激素及其受体在痛觉调节中作用的研究进展
Progresses in the study of corticotropin releasing factor (CRF) and CRF receptor,their roles in the regulation of pain
摘要
最近的大量研究表明 ,促肾上腺皮质激素释放激素 (CRF)和CRF类似肽广泛分布于脑、脊髓和内脏器官。CRF和CRF类似肽均可与CRF受体结合。CRF受体 (CRFR)可分为CRFR 1、CRFR 2和CRFR 3三种类型。CRFR 2又分为A、B、C三个亚型。各种CRF受体激活时 ,对细胞产生相应的功能调节。CRF参与机体多层次的痛觉调节 ,CRF。
出处
《生理科学进展》
CAS
CSCD
北大核心
2003年第3期263-265,共3页
Progress in Physiological Sciences
基金
国家自然科学基金 (39970 10 5 )资助课题
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