摘要
目的 :研究 4种不同纯化方法对大黄提取液中总蒽醌富集的效果。方法 :以纯化液的固体物收率和总蒽醌的含量为指标 ,对明胶沉淀法、醇调 pH值法、聚酰胺法以及大孔吸附树脂法的纯化作用进行比较。 结果 :4种纯化方法所得纯化液的固体物收率明显降低 ,而对总蒽醌的保留率具有显著的差异 ,以ResinⅠ、Ⅱ两种大孔吸附树脂最高 (93.2 1% ,95 .6 3% )。结论 :大孔吸附树脂对大黄总蒽醌具有较强的富集作用。
Objective: To study the effects of four separation and purification methods on total anthraquinone content in Radix et Rhizoma Rhei decoction. Methods: To Compare the purification efficiency of four methods: gelatim precipition, pH adjustment, polyamide adsorption and macropurous resin adsoption, solid content and total anthraquinone in Radix et Rhizoma Rhei decoction were selected as markers. Results: All solid content of Radix et Rhizoma Rhei decoction greatly decreased after purification while the total anthraquinone content was varied from one method to another. The total anthraquinone content retention rate of macroporous adsorption resin Ⅰ and Ⅱ were highest ( 93.21% , 95.63% respectively). Conclusion: Macropurous adsorption resin have a good enriching effect on the separation and purification of total anthraquinone in Radix et Rhizoma Rhei decoction.
出处
《中成药》
CAS
CSCD
北大核心
2003年第10期783-785,共3页
Chinese Traditional Patent Medicine
基金
四川省重点科技项目 :中药制剂现代化研究 (批准号 :0 1SG0 0 8 0 1)
关键词
大黄
大黄总葸醌
纯化
大孔吸附树脂
Radix et Rhizoma Rhei
total anthraquinone
purification
macroporous adsorption resin
