1Pantel K, Dickmanns A, Zipplius A, et al. Estabishment of micrometastatic carcimomn cell lines: a novel source of tumor cell vaccines. J Natl cancer Inst,1995,87: 1162-1168.
2Melchior SW. Corey E. Ellis W J, et al. Early tumor cell aissmination in patients with clinically localized carcionma of prostate. Clin Cancer Res, 1997, 2; 249-256.
3Moll R. Franke WW, Schiller DL, et al. The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. Cell, 1982, 21: 11-24.
4Adell G. Boeryd B. Franlund B, et al. occurrence and prognostic importance of micrometastases in regional lymph nodes in dukes B colorectal carcinoma: an immunohistochemical study, Eur J surg, 1996, 162: 637-642.
5Calaluce R. Miedema BM, Yesus YW. micrometastasis in colorectal cercinoma : a review, J Surg Oncol, 1998,67: 194-202.
6Takeda S, Lchii S. Nakamura Y. Detection of K-ras mutation in sputum by mutant-all elespecific amplification (MASA). Hun Mutat, 1993, 2:112-117.
7Hayashi N. Ito I, Yanagisawa A. et al. Genetic diagnosis of lymph-node metastasis in colorectal cancer. Lancet,1995, 345: 1257-1259.
8Nakamoris, Kameyama M, Furukawa H, et al. Genetic detection of colorectal cancer cellsin circulation and lymph modes, dis colon Rectum, 1997. S29-36.
9Liefers GJ. Cleton JA, Vande Velde, et al. Micrometastases and survival in stage Ⅱ colorectal cancer. N Engl J Med, 1998, 339: 223-228.
10Mori M, Mimori K, Lnoue H, et al. Detection of cancer micrometastases in lymph nodes by reverse transcriptase-polymerase chain reaction. Cancer Res, 1995, 55:3417-3420.