摘要
目的 探讨丙型肝炎患者血清 TNF-α、IL - 6、IL - 8含量的变化。方法 分别采用放免法和酶联吸附法对 5 8例丙型肝炎患者进行了血清 TNF- α和 IL- 6、IL- 8含量检测 ,并与 3 5名正常健康人作对照。结果 丙型肝炎患者血清 TNF-α、IL - 6、IL - 8水平均高于正常人组 ( P<0 .0 1) ,且与肝功检测指标 AL T、TBil含量改变呈正相关。结论 检测丙型肝炎患者血清 TNF- α、IL- 6及 IL-
Objective To explore the changes of serum TNF-α?IL-6?IL-8 levels in patients wiht hepatitis C.Methods Levels of serum TNF-α was detected by RIA,IL-6 and IL-8 by ELISA in 58 cases of hepatitis C and 35 normal controls.Results Serum levels of TNF-α?IL-6 and IL-8 were higher than those in normal controls(P< 0.01),There were positive correlation between serum levels of TNF-α,IL-6 and IL-8 and serum ALT and total bilirubin.Conclusion Serum levels of TNF-α,IL-6 and IL-8 in patients with hepatitis C are related to immune function injury degree of liver.
出处
《淮海医药》
2003年第2期106-107,共2页
Journal of Huaihai Medicine
