摘要
本试验进行了头孢噻呋晶体注射液弃奶期验证研究。试验选用20头健康泌乳奶牛,以推荐剂量每千克体重6.6mg,单次皮下注射头孢噻呋晶体注射液,于给药后8h、24h和32h分别采集奶样,使用经验证的分析方法测定牛奶中头孢噻呋残留浓度,依据头孢噻呋在牛奶中的最高残留限量,确定头孢噻呋晶体注射液的弃奶期为0日。
This experiment was conducted to verify the withdrawal period of ceftiofur crystalline free acid injection in milk.Twenty healthy cows were selected in the experiment,the recommended dose was 6mg/kg bw,single subcutaneous injection,and collected the milk on 8h,24h or 32h after administration.The residual concentration of ceftiofur crystalline free acid in each collected sample was determined by a proven analytical method.According to the maximum residue limit of ceftiofur crystalline free acid in milk,the withdrawal period of ceftiofur crystalline free acid in milk was determined to be zero days.
作者
冯言言
郑莉
杨智国
马庆祝
陈玲
常雪
李龙飞
郭晶晶
孔梅
FENG Yan-yan;ZHENG Li;YANG Zhi-guo;MA Qing-zhu;CHEN Ling;CHANG Xue;LI Long-fei;GUO Jing-jing;KONG Mei(Qilu Animal Health Products Co.,Ltd,Jinan 250100;Shandong Animal Products Quality and Safety Center,Jinan 250100;Shandong Center for Quality Control of Feed and Veterinary Drugs,Jinan 250100)
出处
《中国奶牛》
2025年第3期21-24,共4页
China Dairy Cattle
基金
“十四五”国家重点研发计划项目“抗菌药新型载药系统及制剂技术研究”课题(2023YFD1800901)。
关键词
头孢噻呋晶体注射液
牛奶
弃奶期验证
Ceftiofur crystalline free acid injection
Cows
Verification of withdrawal period