摘要
目的:分析瑞芬太尼复合丙泊酚靶控输注麻醉在鼻内镜手术中的应用效果。方法:选取2022年3月—2024年3月山东大学中西医结合医院收治的92例鼻内镜手术患者,随机分为两组,各46例。观察组行瑞芬太尼复合丙泊酚靶控输注麻醉,对照组行瑞芬太尼复合依托咪酯静脉输注麻醉。对比两组躁动发生率、疼痛程度、苏醒质量、血流动力学、不良反应。结果:观察组躁动发生率为4.35%(2/46),低于对照组的17.39%(8/46),差异有统计学意义(χ^(2)=4.039,P=0.045)。术后4 h、12 h、24 h,观察组视觉模拟评分法(VAS)评分低于对照组,差异有统计学意义(P<0.05)。观察组自主呼吸恢复时间、拔管时间、睁眼时间和麻醉后监测治疗室(PACU)停留时间均显著优于对照组,差异有统计学意义(P<0.05)。术毕时(T0),两组平均动脉压(MAP)、心率(HR)比较,差异无统计学意义(P>0.05);拔管后15 min(T_(1))、出PACU时(T_(2)),观察组MAP、HR低于对照组,差异有统计学意义(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:瑞芬太尼复合丙泊酚靶控输注麻醉可减少鼻内镜手术患者躁动的发生,能减轻术后疼痛,血流动力学指标更优,促进患者苏醒,且无严重不良反应。
Objective:To analyze the effect of Remifentanil combined with Propofol target controlled infusion anesthesia on patients undergoing nasal endoscopic surgery.Method:A total of 92 patients who underwent nasal endoscopic surgery were admitted to Jinan Integrated Traditional Chinese and Western Medicine Hospital from March 2022 to March 2024.They were randomly divided into two groups,with 46 patients in each group.The observation group received target controlled infusion anesthesia with Remifentanil combined with Propofol,while the control group received intravenous infusion anesthesia with Remifentanil combined with Etomidate.The incidence of agitation,degree of pain,awakening quality,hemodynamics,and adverse reactions between two groups were compared.Result:The incidence of agitation in the observation group was 4.35%(2/46),which was lower than 17.39%(8/46)in the control group,the difference was statistically significant(χ^(2)=4.039,P=0.045).At 4 h,12 h and 24 h after operation,visual analogue scale(VAS)scores in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).The recovery time of spontaneous respiration,extubation time,eye opening time and postanesthesia care unit(PACU)residence time in the observation group were significantly better than those in the control group,the differences were statistically significant(P<0.05).There were no significant differences in mean arterial pressure(MAP),heart rate(HR)at the end of surgery(T0)between the two groups(P>0.05).At 15 min after extubation(T_(1)),at the time of exit from PACU(T_(2)),MAP and HR in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Remifentanil combined with Propofol target controlled infusion anesthesia can reduce the incidence of agitation in patients undergoing endoscopic sinus surgery,alleviate postoperative pain,and the hemodynamic indicators is better,which can promote patient recovery,and cause no severe adverse reactions.
作者
陈丽荣
CHEN Lirong(Jinan Integrated Traditional Chinese and Western Medicine Hospital,Jinan 271100,China)
出处
《中外医学研究》
2025年第7期126-129,共4页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
鼻内镜手术
瑞芬太尼
血流动力学
躁动
不良反应
Nasal endoscopic surgery
Remifentanil
Hemodynamics
Agitation
Adverse reactions
