摘要
目的:探讨自拟“尿淋方”联合盐酸坦洛新缓释胶囊治疗双J管相关不良反应的疗效。方法:收集符合标准的90例留置单侧双J管患者,90例患者按随机分组原则分为三组,每组30例,A组为空白对照组,B组为西药治疗组,C组为中西医结合治疗组。A组患者留置双J管期间不使用药物干预;B组患者留置双J管期间口服盐酸坦洛新缓释胶囊0.2mg,1次/d;C组患者留置双J管期间在口服盐酸坦洛新缓释胶囊0.2mg,1次/d基础上,加用自拟尿淋方。所有患者在拔除导尿管后第2天、术后第2周、拔除双J管前,分别记录VAS评分(视觉模拟评分法)、IPSS评分(国际前列腺症状评分)、QOL评分(生活质量指数评分),并检查尿常规,记录尿液红细胞及白细胞数目。结果:87例患者最终顺利根据治疗方案完成实验和随访,另3例患者因未按时随访及未按时服药等原因退出。中西医结合治疗组各阶段的VAS评分、IPSS评分及QOL评分均优于单用西药治疗组及空白对照组,差异有统计学意义(P<0.05)。且中西医结合治疗组在各阶段检查尿常规中白细胞及红细胞数目,均少于空白对照组及西药治疗组,差异具有统计学意义(P<0.05)。结论:使用自拟“尿淋方”联合盐酸坦洛新缓释胶囊治疗双J管相关不良反应疗效较好。
Objective:To explore the efficacy of self-prescribed“Niailin prescription”combined with tamsulosin hydrochloride sustained-release capsules in the treatment of double J tube-related adverse reactions.Methods:A total of 90 patients with unilateral double J tube who met the criteria were enrolled and randomly divided into three groups,30 cases in each group.Group A was the blank control group,group B was the western medicine treatment group,and group C was the integrated Chinese and Western medicine treatment group.No drug intervention was used in group A patients during the period of double J tube indwelling;group B patients took 0.2 mg of tamsulosin hydrochloride sustained-release capsules orally once a day(qd)during the period of double J tube indwelling;group C patients took selfprescribed“Niailin prescription”on the basis of taking 0.2 mg of tamsulosin hydrochloride sustained-release capsules orally qd during the period of double J tube indwelling.On the second day after the removal of the urinary catheter,the second week after surgery,and before the removal of the double J tube,the VAS score(visual analog scale),IPSS score(international prostate symptom score),QOL score(quality of life index score)were recorded for all patients,and urine routine examination was performed,and the number of red blood cells and white blood cells in urine was recorded.Results:87 patients finally completed the experiment and follow-up according to the treatment plan,and the other 3 patients withdrew due to reasons such as failure to follow up on time and failure to take medication on time.The VAS score,IPSS score and QOL score of the combined Chinese and Western medicine treatment group at each stage were better than those of the Western medicine treatment group and the blank control group,and the difference was statistically significant(P<0.05).In addition,the number of white blood cells and red blood cells in urine routine examination in the combined Chinese and Western medicine treatment group at each stage was less than that of the blank control group and the Western medicine treatment group,and the difference was statistically significant(P<0.05).Conclusion:The self-made“Niaolin Recipe”combined with tamsulosin hydrochloride sustained-release capsules has a good effect in treating double-J catheter-related adverse reactions.
作者
余学理
钟观宝
潘培英
覃桂强
卢永亮
YU Xueli;ZHONG Guanbao;PAN Peiying;QIN Guiqiang;LU Yongliang(Qingyuan Hospital of Traditional Chinese Medicine,Guangdong Qingyuan 511500,China)
出处
《中医药临床杂志》
2025年第2期364-368,共5页
Clinical Journal of Traditional Chinese Medicine
基金
2021年度广东省中医药局科研项目(20212294)。
关键词
尿淋方
盐酸坦洛新缓释胶囊
双J管
不良反应
Niolin Recipe
Tamsulosin hydrochloride sustained-release capsules
Double-J catheter
Adverse reactions
