摘要
目的 探讨3D旋转数字减影血管造影(DSA)导引在椎动脉起始部狭窄(VAOS)患者药物球囊预扩张裸金属支架治疗中的应用效果。方法 选取2020年5月至2022年12月海安市人民医院收治的63例VAOS患者作为研究对象,按照不同治疗方法将其分为观察组(n=30)和对照组(n=33):观察组男16例,女14例,年龄(52.10±3.62)岁;对照组男19例,女14例,年龄(52.47±3.85)岁。2组患者基础资料比较差异无统计学意义(P>0.05)。观察组采取3D旋转DSA导引下药物球囊预扩张裸金属支架治疗,对照组采取常规药物球囊预扩张裸金属支架治疗,比较2组患者疗效。结果 观察组手术成功率100%(30/30)与对照组96.97%(32/33)比较,差异无统计学意义(χ^(2)=0.924,P=0.336)。术前、术后3个月,2组患者狭窄率比较差异无统计学意义(P>0.05)。术后3个月,观察组椎动脉起始段的血流动力学水平、神经功能评分、生活质量评分低于对照组(P<0.05)。术后6个月,观察组循环卒中事件发生率低于对照组(P<0.05)。观察组有2例(占比6.67%)发生再狭窄,对照组有9例(占比27.27%)发生再狭窄,差异有统计学意义(χ^(2)=4.630,P=0.031)。结论 采取3D旋转DSA导引下药物球囊预扩张裸金属支架治疗能有效降低狭窄率和再狭窄发生率,改善神经功能,提高患者生活质量。
Objective To investigate the effect of 3D rotational digital subtraction angiography(DSA)-guided drug balloon predilation bare-metal stents on vertebral artery origin stenosis(VAOS).Methods A total of 63 VAOS patients who were admitted to Hai’an People’sHospital from May 2020 to December 2022 were selected and divided into two groups according to different treatment methods.There were 16 males and 14 females with a mean age of(52.10±3.62)years in the observation group.There were 19 males and 14 females with a mean age of(52.47±3.85)years in the control group.There was no statistical difference in the basic data between the two groups(P>0.05).The observation group was treated with 3D rotational DSA-guided drug balloon predilation bare-metal stent,while the control group was treated with conventional drug balloon predilation bare-metal stent.The efficacy of the two groups was compared.Results The success rate of operation was 100%(30/30)in the observation group,which was higher than that in the control group(96.97%[32/33],χ^(2)=0.924,P=0.336).There was no significant difference in the stenosis rate between the two groups either before surgery or 3 months after surgery(P>0.05).The hemodynamic level of the initial segment of vertebral artery in the observation group was lower than that in the control group 3 months after surgery(P<0.05).The scores of neurological function and quality of life at 3 months after surgery and the incidence of recurrent stroke at 6 months after surgery in the observation group were lower than those in the control group(P<0.05).Restenosis occurred in 2 cases(6.67%)in the observation group and 9 cases(27.27%)in the control group,and there was significant difference in the incidence of restenosis between the two groups(χ^(2)=4.630,P=0.031).Conclusion 3D rotational DSA-guided drug balloon predilation bare-metal stent can effectively reduce the stenosis rate and the incidence of restenosis,and improve the nerve function and the quality of life of VAOS patients.
作者
张为
范恒亮
周志明
Zhang Wei;Fan Hengliang;Zhou Zhiming(Department of Catheterization Laboratory,Hai’an People’s Hospital,Nantong 226600,China)
出处
《海军医学杂志》
2025年第1期27-31,共5页
Journal of Navy Medicine
基金
江苏省卫生健康委项目(M2020041)。
关键词
3D旋转数字减影血管造影
椎动脉起始部狭窄
药物球囊预扩张
裸金属支架
3D rotational digital subtraction angiography
Vertebral artery origin stenosis
Drug balloon predilation
Bare-metal stent
