摘要
认知灵活性是指个体能够迅速适应不断变化的环境,并在这个过程中迅速切换思维模式并产生适应行为反应的能力。在阿尔茨海默病、帕金森病和肌萎缩侧索硬化等神经退行性疾病中可以观察到患者灵活转变自身心理过程和行为以适应环境变化的能力显著下降(即认知灵活性受损)。本文旨在回顾并总结以往关于神经退行性疾病认知灵活性的行为学评估方法和影像学研究进展,为神经退行性疾病引起的认知灵活性减退的诊断和治疗提供理论基础。
Cognitive flexibility refers to the individual to be able to quickly adapt to changing circumstances,and in the process to switch quickly thinking mode and the ability of adaptation in response.In neurodegenerative diseases such as Alzheimer's disease,Parkinson's disease and amyotrophic lateral sclerosis can be observed in the patients with flexibly shift their own mental processes and behavior to adapt the environment change ability dropped significantly(i.e,impaired cognitive flexibility).This article aims to review and summarize the previous research progress on behavioral assessment methods and imaging studies of cognitive flexibility in neurodegenerative diseases,so as to provide a theoretical basis for the diagnosis and treatment of cognitive flexibility decline caused by neurodegenerative diseases.
作者
曹馨予
于瀛
胡博
颜林枫
崔光彬
CAO Xinyu;YU Ying;HU Bo;YAN Linfeng;CUI Guangbin(Medical School of Yan'an University,Yan'an 716000,China;Department of Radiology,Functional and Molecular Imaging Key Lab of Shaanxi Province,Tangdu Hospital,Air Force Medical University,Xi'an 710038,China)
出处
《磁共振成像》
CAS
CSCD
北大核心
2024年第11期148-152,共5页
Chinese Journal of Magnetic Resonance Imaging
基金
国家自然科学基金项目(编号:82302148)。
关键词
认知灵活性
神经退行性疾病
磁共振成像
阿尔茨海默病
帕金森病
威斯康星卡片分类测试
cognitive flexibility
neurodegenerative diseases
magnetic resonance imaging
Alzheimer's disease
Parkinson's disease
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