摘要
目的:分析冠状动脉狭窄患者冠状动脉CT血管成像(CCTA)的血管及斑块特征。方法:选取2022年10月—2023年9月于上海市金山区亭林医院进行CCTA检查的84例疑似冠心病患者作为研究对象,根据血流储备分数(FFR)检查结果分组,FFR≤0.80为缺血组(n=41),FFR>0.80为非缺血组(n=43)。患者均进行CCTA检查,比较两组血管特征(管腔狭窄程度、受累血管、病变部位)及斑块特征[斑块长度、总斑块体积、总斑块负荷、钙化斑块体积(CPV)、纤维斑块体积(FPV)、低密度斑块体积、弥散病变]。结果:缺血组管腔狭窄程度高于非缺血组(P<0.001);缺血组受累血管主要位于左前降支、左回旋支,非缺血组受累血管主要位于为左前降支、右冠状动脉(P=0.037);两组病变部位比较,无统计学差异(P>0.05)。缺血组斑块长度、CPV、FPV大于非缺血组,弥散病变发生率高于非缺血组(P<0.05);两组总斑块体积、总斑块负荷、低密度斑块体积比较,差异无统计学意义(P>0.05)。结论:冠状动脉狭窄缺血患者与非缺血患者CCTA的血管狭窄程度、受累血管分布和斑块特征均存在差异,可能与血管的解剖结构、血流动力学特征、斑块的组成和分布及炎性反应等因素有关。
Objective:To analyze the characteristics of blood vessels and plaques in patients with coronary stenosis by coronary CT angiography(CCTA).Methods:A total of 84 patients with suspected coronary heart disease who completed CCTA examination in Shanghai Jinshan District Tinglin Hospital from October 2022 to September 2023 were selected as the study subjects.Accord-ing to the results of fractional flow reserve(FFR)examination,patients with FFR≤0.80 were included as ischemic group(n=41)and patients with FFR>0.80 were included as non-ischemic group(n=43).All patients underwent CCTA examination.The char-acteristics of blood vessels(degree of lumen stenosis,the involved vessels,and location of lesions)and plaques[plaque length,to-tal plaque volume,total plaque load,calcified plaque volume(CPV),fibrous plaque volume(FPV),low-density plaque volume,dif-fuse lesions]were compared between the two groups.Results:The degree of lumen stenosis in the ischemic group was higher than that in the non-ischemic group(P<0.001);the involved vessels in the ischemic group were mainly located in the left anterior de-scending branch and the left circumflex branch,while the involved vessels in the non-ischemic group were mainly located in the left anterior descending branch and the right coronary artery(P=0.037);there was no statistical difference in the lesion site between the two groups(P>0.05).The length of plaques,CPV and FPV in the ischemic group were greater than those in the non-ischemic group,and the incidence of diffuse lesions in the ischemic group was higher than that in the non-ischemic group(P<0.05);there was no statistical difference in the total plaque volume,total plaque load and low-density plaque volume between two groups(P>0.05).Conclusion:There are differences in the degree of vascular stenosis,distribution of involved vessels,and plaque charac-teristics by CCTA between ischemic and non-ischemic patients with coronary artery stenosis,which may be related to factors such as vascular anatomical structure,hemodynamic characteristics,plaque composition and distribution,and inflammatory reactions.
作者
陆浩宇
张秋凤
陈文静
王永胜
Lu Haoyu;Zhang Qiufeng;Chen Wenjing;Wang Yongsheng(Shanghai Jinshan District Tinglin Hospital,Shanghai 201505,China)
出处
《中国社区医师》
2024年第36期86-88,共3页
Chinese Community Doctors
