摘要
目的分析温针灸联合羌防祛痹汤治疗寒湿痹阻型膝关节骨性关节炎的临床效果。方法选取2020年8月—2022年10月收治的膝关节骨性关节炎(寒湿痹阻型)患者70例作为研究对象,采用随机数字表法分为参照组与研究组,每组35例。参照组予常规西药,研究组在此基础上加用温针灸联合羌防祛痹汤,比较两组临床效果和治疗前后血清白细胞介素-1β(IL-1β)、基质金属蛋白酶9(MMP-9)、破骨细胞抑制因子(OPG)、碱性磷酸酶(ALP)水平及膝关节功能评分。结果研究组治疗总有效率为94.29%(33/35),高于参照组的71.43%(25/35)(P<0.05)。治疗后,研究组IL-1β、MMP-9水平低于参照组,OPG、ALP水平高于参照组,膝关节功能评分亦高于参照组(P<0.05)。结论温针灸联合羌防祛痹汤治疗寒湿痹阻型膝关节骨性关节炎效果较显著,能有效改善患者炎症情况,促进其膝关节功能恢复。
Objective To analyze the clinical effect of warming needle moxibustion combined with Qiangfang Qubi decoction in the treatment of knee osteoarthritis of cold-dampness blockade type.Methods A total of 70 patients with knee osteoarthritis of colddampness blockade type from August 2020 to October 2022 were selected as research objects,and were divided into control group and study group by random number table method,with 35 cases in each group.The control group was treated with conventional Western medicine,and the study group was treated with warming needle moxibustion combined with Qiangfang Qubi decoction.The total effective rate,serum interleukin 1β(IL-1β),matrix metalloproteinase 9(MMP-9),serum osteoclast inhibitor(OPG),alkaline phosphatase(ALP)and knee function scores before and after treatment were compared between the two groups.Results The total effective rate of the study group was 94.29%(33/35),which was higher than that of the control group(71.43%,25/35)(P<0.05).After treatment,the levels of IL-1βand MMP-9 in the study group were lower than those in the control group,the levels of OPG and ALP were higher than those in the control group,and the knee function score was also higher than that in the control group(P<0.05).Conclusion The combination of warming needle moxibustion with Qiangfang Qubi decoction is effective in the treatment of knee osteoarthritis of colddampness blockade type,can effectively improve the inflammation of patients and promote the recovery of knee joint function.
作者
黄悦
李玲
HUANG Yue;LI Ling(Department of Orthopedics,Nanchang Hongdu Hospital of Traditional Chinese Medicine,Jiangxi Province,Nanchang 330000,China)
出处
《中国中医药现代远程教育》
2025年第1期150-152,共3页
Chinese Medicine Modern Distance Education of China
关键词
痹证
膝关节骨性关节炎
寒湿痹阻证
羌防祛痹汤
温针灸疗法
arthralgia syndrome
knee osteoarthritis
cold-dampness blockade syndrome
Qiangfang Qubi decoction
warming needle moxibustion
