摘要
目的:探讨逍遥散加减治疗中重度痤疮的具体效果,并分析该治疗方法对患者血清辅助性T细胞1(Th1)/Th2型细胞因子所产生的具体作用。方法:选取在我院2022年3月~2024年3月接受治疗的70例中重度痤疮患者作为研究对象,将70例患者平均分为两个组,每组35例患者,分别命名为对照组及观察组。对照组患者采取脉冲染料激光治疗,在此基础上,对观察组患者实行逍遥散加减治疗方式。经一段时间治疗后,对比两组患者的治疗有效率、治疗前后的痤疮症状评分、血清辅助性T细胞1(Th1)/Th2型细胞因子水平及不良反应发生概率。结果:观察组的治疗有效率结果相较于对照组更高;经过不同治疗方式后,观察组的痤疮症状评分更低,明显低于对照组;观察组在治疗后痤疮症状评分均低于对照组;观察组T细胞1(Th1)/Th2型细胞因子水平均优于对照组;观察组在治疗后发生不良反应的情况较少,发生概率低于对照组。结论:逍遥散加减治疗中重度痤疮患者具有明显的正向效果,能够有效缓解患者的痤疮症状,同时具有较高的安全性,值得临床应用。
Objective:To explore the specific effects of modified Xiaoyao San in the treatment of moderate to severe acne,and analyze the specific effects of this treatment method on the production of serum helper T cell 1(Th1)/Th2cytokines in patients.Method:70patients with moderate to severe acne who received treatment in our hospital from March 2022to March 2024were selected as the research subjects.The 70patients were evenly divided into two groups,with 35patients in each group,named the control group and the observation group,respectively.The control group patients were treated with pulsed dye laser,while the observation group received modified treatment with Xiaoyao Powder on the basis of the control group treatment plan.After a period of treatment,the specific treatment effects,acne symptom scores before and after treatment,serum levels of Th1/Th2cytokines,and the probability of adverse reactions were compared between the two groups of patients.Result:The treatment effect of the observation group was higher than that of the control group;the observation group had lower acne symptom scores than the control group after treatment;the levels of Th1/Th2cytokines in the observation group were superior to those in the control group;the observation group had fewer adverse reactions after treatment,and the probability of occurrence was lower than that of the control group.Conclusion:Xiaoyao San has a significant positive effect in the treatment of moderate to severe acne patients,effectively alleviating their acne symptoms,and has high safety,which is worthy of clinical application.
作者
姚荣
胡博
任雪雯
邓宇童
孟醒
YAO Rong;HU Bo;REN Xuewen(Department of Dermatology,Dongfang Hospital,Beijing University of Traditional Chinese Medicine,Beijing 100078,China)
出处
《四川中医》
2024年第12期166-168,共3页
Journal of Sichuan of Traditional Chinese Medicine
基金
北京“十四五”中医药重点专科项目(编号:BJZKBC0015)。
关键词
逍遥散加减
中重度痤疮
血清辅助性T细胞
Xiaoyao San with modifications
Moderate to severe acne
Serum helper T cells
