摘要
目的了解杭州市2016—2022年新报告的经异性性传播感染的HIV感染者和艾滋病患者(HIV/AIDS)的感染特征及晚发现状况, 为HIV经异性性传播的防制提供依据。方法收集2016—2022年中国疾病预防控制信息系统中异性性传播病例信息, 对人群的感染特征进行描述性分析。应用单因素和多因素Logistic回归分析晚发现的影响因素。结果共有2 967例病例经异性性传播感染HIV, 晚发现病例1 288例(43.41%)。多因素Logistic回归结果显示, 与经配偶传播感染相比, 男性(OR=9.58, 95%CI: 6.44~14.27), <30岁(OR=4.53, 95%CI: 2.11~9.75)、30~39岁(OR=3.94, 95%CI: 2.31~6.73)、40~49岁(OR=2.93, 95%CI: 1.77~4.84)、50~59岁(OR=1.70, 95%CI: 1.12~2.57), 离异或丧偶(OR=9.45, 95%CI: 5.75~15.53)、未婚(OR=6.67, 95%CI: 2.95~15.10)的非婚非商业性行为感染HIV的风险更高;男性(OR=244.79, 95%CI: 146.08~410.20), 30~39岁(OR=2.51, 95%CI: 1.39~4.51)、40~49岁(OR=2.19, 95%CI: 1.26~3.78), 离异或丧偶(OR=9.11, 95%CI: 5.36~15.47)、未婚(OR=4.95, 95%CI: 2.13~11.52)的商业性行为感染HIV的风险更高。多因素Logistic回归显示晚发现的主要影响因素包括非婚非商业性传播(OR=1.62, 95%CI: 1.17~2.25)、女性(OR=0.71, 95%CI: 0.58~0.88)、30~39岁(OR=1.62, 95%CI: 1.23~2.15)、40~49岁(OR=2.78, 95%CI: 2.03~3.80)、50~59岁(OR=2.26, 95%CI: 1.63~3.13)、≥60岁(OR=2.97, 95%CI: 2.09~4.21)和医疗机构检测发现(OR=1.83, 95%CI: 1.38~2.43)。结论杭州市通过异性性传播感染的HIV/AIDS晚发现比例高。应关注中老年人的商业性行为与青壮年的非婚非商业性行为。
Objective:To explore epidemiological characteristics and situation of late diagnosis among newly reported HIV/AIDS cases through heterosexual transmission from 2016 to 2022,so as to provide evidence for the prevention and control of HIV heterosexual transmission in Hangzhou.Methods:Information of newly reported HIV/AIDS cases between 2016 and 2022 was collected from National Comprehensive HIV/AIDS Information System.Descriptive epidemiological method was accessed to analyze sociodemographic characteristics.The influential factors of late diagnosis among these HIV/AIDS cases were analyzed by univariate and multivariate Logistic regression model.Results:There were 2967 HIV/AIDS cases infected by heterosexual transmission,including 1288 late diagnosed cases(43.41%).Multivariate Logistic regression analysis revealed that male(OR=9.58,95%CI:6.44-14.27),<30 years old(OR=4.53,95%CI:2.11-9.75),30-39 years old(OR=3.94,95%CI:2.31-6.73),40-49 years old(OR=2.93,95%CI:1.77-4.84),50-59 years old(OR=1.70,95%CI:1.12-2.57),divorced or widowed(OR=9.45,95%CI:5.75-15.53),unmarried(OR=6.67,95%CI:2.95-15.10)were influencing factors of HIV infection through non-marital and non-commercial heterosexual transmission compared to HIV infection through spousal contact.Male(OR=244.79,95%CI:146.08-410.20),30-39 years old(OR=2.51,95%CI:1.39-4.51),40-49 years old(OR=2.19,95%CI:1.26-3.78),divorced or widowed(OR=9.11,95%CI:5.36-15.47)unmarried(OR=4.95,95%CI:2.13-11.52)were influencing factors of HIV infection through commercial heterosexual transmission.Multivariate Logistic regression analysis on late diagnosis showed that non-marital and non-commercial heterosexual transmission(OR=1.62,95%CI:1.17-2.25),female(OR=0.71,95%CI:0.58-0.88),30-39 years old(OR=1.62,95%CI:1.23-2.15),40-49 years old(OR=2.78,95%CI:2.03-3.80),50-59 years old(OR=2.26,95%CI:1.63-3.13),≥60 years old(OR=2.97,95%CI:2.09-4.21),detected in medical institutions(OR=1.83,95%CI:1.38-2.43)were influencing factors for late diagnosis.Conclusions:The proportion of late diagnosis among HIV/AIDS cases infected through non-marital heterosexual transmission in Hangzhou is relatively high.Attention should be given to the commercial heterosexual transmission among the elderly,as well as the non-marital and non-commercial heterosexual transmission among young populations.
作者
黄思超
许珂
刘盼盼
陈珺芳
Huang Sichao;Xu Ke;Liu Panpan;Chen Junfang(Department of AIDS/STDs Control and Prevention,Hangzhou Center for Disease Control and Prevention(Hangzhou Health Supervision Institution),Hangzhou 310021,China)
出处
《国际流行病学传染病学杂志》
CAS
2024年第5期334-340,共7页
International Journal of Epidemiology and Infectious Disease
基金
浙江省医药卫生科技计划(2024KY1416)。
