摘要
目的了解某单位中青年男性血脂异常的发病情况及其危险因素,为其预防和干预提供参考依据。方法收集2019年1月至2020年12月来某疗养机构进行疗养的某单位中青年男性的体检数据,采用χ^(2)检验对血脂异常检出率分布特征进行分析,采用多因素Logistics回归分析血脂异常的危险因素。结果956例中青年男性检出209例血脂异常,检出率为21.9%。高胆固醇(TC)血症、高三酰甘油(TG)血症、高低密度脂蛋白胆固醇(LDL-C)血症和低高密度脂蛋白胆固醇(HDL-C)血症的检出率分别为6.1%、12.4%、0.4%、10.4%。血脂异常随着年龄的增加呈上升趋势(P<0.05);随着体质指数(body mass index,BMI)的增加,血脂异常检出率增高(P<0.05)。多因素Logistics回归分析结果显示,年龄(OR=1.047,95%CI:1.017,1.078)、超重(OR=2.208,95%CI:1.506,3.238)、肥胖(OR=4.121,95%CI:2.032,8.355)、丙氨酸氨基转移酶(alanine transaminase,ALT)异常(OR=2.353,95%CI:1.568,3.530)、脂肪肝(OR=1.674,95%CI:1.116,2.511)和高尿酸血症(OR=2.468,95%CI:1.733,3.515)是血脂异常的危险因素(P<0.05)。结论年龄、超重、肥胖、ALT异常、脂肪肝和高尿酸血症均是某单位中青年男性血脂异常的危险因素,除了年龄,其他都与不良的饮食和生活习惯相关。因此,降低脂肪、嘌呤的摄入量和科学进行身体锻炼控制BMI是预防和干预血脂异常的有效措施。
Objective To understand the incidence and risk factors of dyslipidemia in young and middle-aged men in a certain unit,so as to provide reference for its prevention and intervention.Methods The physical examination data of young and middle-aged men in a certain unit coming to a convalescent institution for recuperation from January 2019 to December 2020 were collected.The distribution characteristics of the detection rate of dyslipidemia were analyzed byχ^(2) test,and the risk factors of dyslipidemia were analyzed by multi-factor Logistics regression.Results In 956 young and middle-aged men,209 cases were detected with dyslipidemia,the detection rate was 21.9%.The detection rates of hypercholesterolemia,hypertriglyceridemia,high-low density lipoprotein cholesterol(LDL-C)and low-high density lipoprotein cholesterol(HDL-C)were 6.1%,12.4%,0.4%and 10.4%,respectively.Dyslipidemia increased with age(P<0.05).With the increase of body mass index(BMI),the detection rate of dyslipidemia increased(P<0.05).The results of multi-factor Logistics regression analysis showed that age(OR=1.047,95%CI:1.017,1.078),overweight(OR=2.208,95%CI:1.506,3.238),obesity(OR=4.121,95%CI:2.032,8.355),abnormal alanine transaminase(ALT)(OR=2.353,95%CI:1.568,3.530),fatty liver(OR=1.674,95%CI:1.116,2.511)and hyperuricemia(OR=2.468,95%CI:1.733,3.515)were risk factors for dyslipidemia(P<0.05).Conclusion Age,overweight,obesity,abnormal ALT,fatty liver and hyperuricemia are all risk factors for dyslipidemia in young and middle-aged men.Except age,other factors are related to poor diet and lifestyle habits.Therefore,reducing the intake of fat and purine and scientifically exercising to control BMI are effective measures to prevent and intervene in dyslipidemia.
作者
黄蓉妮
熊毅
鲁华山
邓佑兴
秦金花
涂瑶伟
HUANG Rong-ni;XIONG Yi;LU Hua-shan;DENG You-xing;QIN Jin-hua;TU Yao-wei
出处
《中国疗养医学》
2024年第12期10-14,共5页
Chinese Journal of Convalescent Medicine
关键词
血脂异常
中青年男性
影响因素
Dyslipidemia
Young and middle-aged men
Influencing factor