摘要
目的:分析受血者输血前检测感染性疾病指标的结果与临床意义。方法:选取2020年1月—2023年6月在永州市第三人民医院接受输血治疗的受血者1379例为研究对象。所有受血者输血前检测乙肝表面抗原(HBSAg)、人类免疫缺陷病毒抗体(抗-HIV)、丙型肝炎病毒抗体(抗-HCV)、梅毒螺旋体特异性抗体(抗-TP)、丙氨酸氨基转移酶(ALT)水平。分析感染性疾病指标结果并探讨其临床意义。结果:1379例受血者中,感染性指标检测结果阳性者共101例,阳性检出率为7.32%,其中HBSAg阳性检出率最高,为4.57%。784例男性受血者中,感染性指标检测结果阳性者共57例,阳性检出率为7.27%;595例女性受血者中,感染性指标检测结果阳性者共44例,阳性检出率为7.39%。不同性别受血者HBSAg、抗-HIV、抗-HCV、抗-TP、ALT阳性检出率比较,差异无统计学意义(P>0.05)。1272例无输血史受血者中,感染性指标检测结果阳性者共78例,阳性检出率为6.13%;107例有输血史受血者中,感染性指标检测结果阳性者共23例,阳性检出率为21.50%。有输血史受血者HBSAg、抗-HIV、抗-TP、ALT阳性检出率高于无输血史者(P<0.05)。1379例受血者中,多重感染患者27例,总阳性率为1.96%,抗-HIV+HBSAg混合感染率最高,为0.58%。结论:部分受血者患感染性疾病,其中有输血史的受血者阳性检出率高于无输血史者,且存在多重感染情况,输血前进行感染性疾病指标检测有助于为临床加强输血安全监控提供指导。
Objective:To analyze the results and clinical significance of infectious disease index in blood recipients before transfusion.Methods:A total of one thousand three hundred and seventy-nine blood recipients who received transfusion treatment in Yongzhou Third People's Hospital from January 2020 to June 2023 were selected as the study objects.The levels of hepatitis B surface antigen(HBSAg),human immunodeficiency virus antibody(anti-HIV),hepatitis C virus antibody(anti-HCV),treponema pallidum specofoc antibody(anti-TP)and alanine aminotransferase(ALT)were detected in all blood recipients before transfusion.The results of infectious disease indexes were analyzed and their clinical significance was discussed.Results:Among the 1379 blood recipients,101 cases were positive for infection index,the positive detection rate was 7.32%,and the positive detection rate of HBSAg was the highest(4.57%);among 784 male blood recipients,57 cases were positive for infection index,the positive detection rate was 7.27%;among 595 female blood recipients,44 were positive for infection index,the positive detection rate was 7.39%;there was no significant difference in the positive rates of HBSAg,anti-HIV,anti-HCV,anti-TP and ALT among different sex recipients(P>0.05).Among the 1272 patients without blood transfusion history,78 were positive for infection index,the positive detection rate was 6.13%;among 107 patients with blood transfusion history,23 cases were positive for infection index,and the positive detection rate was 21.50%.The positive rates of HBSAg,anti-HIV,anti-TP and ALT in patients with blood transfusion history were higher than those without blood transfusion history(P<0.05).Among the 1379 blood recipients,27 were multiple infection patients,the total positive rate was 1.96%,and the mixed infection rate of anti-HIV+HBSAg was the highest(0.58%).Conclusion:Some blood recipients suffer from infectious diseases,among which the positive detection rate of blood recipients with blood transfusion history is higher than that of those without blood transfusion history,and there are multiple infections.The detection of infectious disease indicators before blood transfusion is helpful to provide guidance for strengthening clinical blood transfusion safety monitoring.
作者
黄宏兰
Huang Honglan(Yongzhou Third People's Hospital,Yongzhou 425000,Hunan Province,China)
出处
《中外医药研究》
2024年第26期138-140,共3页
JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH
关键词
输血
受血者
感染性指标
医源性感染
Blood transfusion
Blood recipient
Infectivity index
Latrogenic infection
