摘要
目的比较不同国家或地区2022年人类发展指数(HDI)与白血病发病率和死亡率的关联,以及不同HDI等级国家白血病发病率和死亡率随年龄变化的趋势。方法根据GLOBOCAN 2022全球不同国家或地区白血病发病和死亡相关数据与HDI进行Pearson相关分析和Kruskal-Wallis检验。各年龄段发病率和死亡率及其随年龄变化趋势使用Joinpoint Regression模型分析。结果四组HDI等级国家的年龄标化发病率(ASIR)、年龄标化死亡率(ASMR)和标化死亡发病比(M/I)的差别具有统计学意义(P<0.001);HDI与全球国家的ASIR和ASMR呈正相关,与M/I呈负相关。在各个年龄段上,四组HDI等级国家的发病率和死亡率随年龄变化具有相似的趋势,且15岁前与40岁后为白血病高发年龄。中国在各个年龄段上白血病发病率与其他高HDI国家有所差异,而死亡率均低于其他高HDI国家。结论HDI高的国家或地区具有更高的ASIR和ASMR,同时由于其具有较好医疗水平,也具有更低的M/I。
Objective To compare the association of the incidence and mortality of leukemia and the human development index(HDI)in different countries or regions in 2022,and the trend of leukemia incidence and mortality with age in countries with different HDI levels.Methods GLOBOCAN 2022 data related to leukemia incidence and mortality in different countries or regions worldwide and HDI were evaluated by Pearson correlation analysis and Kruskal–Wallis test.The incidence and mortality rates of each age and the age change trend were analyzed using the Joinpoint Regression model.Results Age-standardized incidence rate(ASIR),age-standardized mortality rate(ASMR),and mortality to incidence ratio(M/I)were statistically significantly different among the four groups of HDI countries(P<0.001).HDI was positively correlated with ASIR and ASMR and negatively correlated with M/I.Among all ages,ASIR and ASMR of leukemia of the four groups had similar trends with age,and the risk of leukemia was high at ages less than 15 and more than 40.The incidence of leukemia in all age groups in China differed from those in other countries with high HDI,while the mortality rate was lower than those in other countries with high HDI.Conclusion Countries or regions with higher HDI have higher ASIR and ASMR and lower M/I because of their better medical condition.
作者
何奕达
朱小琼
李政
柳东红
曹广文
HE Yida;ZHU Xiaoqiong;LI Zheng;LIU Donghong;CAO Guangwen(Department of Epidemiology,Faculty of Naval Medicine,Naval Medical University,Shanghai Key Laboratory of Medical Bioprotection,Key Laboratory of Biological Defense,Ministry of Education,Shanghai 200433,China;Shanghai Putuo District Center for Disease Control and Prevention,Shanghai 200333,China;Department of Special Medical Care,The Third Affiliated Hospital,Naval Medical University,Shanghai 200438,China)
出处
《肿瘤防治研究》
CAS
2024年第10期870-876,共7页
Cancer Research on Prevention and Treatment
基金
上海市加强公共卫生体系建设三年行动计划(GWVI-11.1-10)。
关键词
白血病
人类发展指数
发病率
死亡率
死亡发病比
Leukemia
Human development index
Incidence rate
Mortality rate
Mortality to incidence ratio
