摘要
目的分析急性ST段抬高型心肌梗死(STEMI)患者经皮冠状动脉介入术(PCI)后发生心肌微循环灌注障碍(MPD)的危险因素。方法队列研究。抽取2018年1月至2022年12月于郑州大学第一附属医院采用PCI治疗STEMI后发生心肌MPD的患者34例作为发生组,并以1∶1配比抽取同期采用PCI治疗STEMI后未发生心肌MPD的患者34例作为未发生组。采集两组患者性别、年龄、体质指数(BMI)、吸烟史、糖尿病史、高血压史、病变分支、Killip分级、梗死相关动脉、置入支架数量、术后心肌梗死溶栓治疗临床试验(TIMI)血流分级、血红蛋白、血小板计数等资料。分析STEMI患者PCI后发生心肌MPD的相关危险因素。结果年龄、糖尿病史、病变分支、术后TIMI血流分级是STEMI患者PCI后发生心肌MPD的影响因素(P<0.05);Logistic回归分析结果显示,年龄>60岁、有糖尿病史、多支病变、术后TIMI血流分级低是STEMI患者PCI后发生心肌MPD的危险因素(P<0.05)。结论STEMI患者PCI后发生心肌MPD的影响因素较多,糖尿病史、多支病变、术后TIMI血流分级低、年龄大等均是影响STEMI患者PCI后发生心肌MPD的危险因素。
ObjectiveTo analyze the risk factors for myocardial microcirculation perfusion disorders(MPD)after percutaneous coronary intervention(PCI)in patients with acute ST elevation myocardial infarction(STEMI).MethodsA total of 34 patients with MPD after PCI for STEMI in the First Affiliated Hospital of Zhengzhou University from January 2018 to December 2022 were selected as the occurrence group of the cohort study,and 34 patients without MPD after PCI for STEMI during the same period were selected as the non-occurrence group at a ratio of 1∶1.Clinical data including gender,age,body mass index,smoking history,diabetes history,hypertension history,lesion branch,Killip classification,infarct-related artery,number of implanted stents,postoperative thrombolysis in myocardial infarction(TIMI)flow grade,hemoglobin,platelet count were collected from both groups.And the risk factors for MPD after PCI in patients with STEMI were analyzed.ResultsAge,diabetes history,lesion branch,postoperative TIMI flow grade were the influencing factors for MPD after PCI in patients with STEMI(P<0.05).Results of Logistic regression analysis showed that age>60 years,diabetes history,multiple vessel lesions,low postoperative TIMI flow grade were the risk factors for MPD after PCI in patients with STEMI(P<0.05).ConclusionsThere are various influencing factors for MPD after PCI in patients with STEMI;diabetes history,multiple vessel lesions,low postoperative TIMI flow grade,and older age are all risk factors for MPD after PCI in patients with STEMI.
作者
吕佳芮
吴蕾
范慧娟
Lyu Jiarui;Wu Lei;Fan Huijuan(Operating Room,Department of Cardiovascular Intervention,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,China)
出处
《中国实用医刊》
2024年第14期37-40,共4页
Chinese Journal of Practical Medicine
