摘要
淋巴瘤相关噬血细胞综合征病情凶险,进展迅速,特别在NK/T细胞淋巴瘤多见。MINE方案为侵袭性非霍奇金淋巴瘤挽救性治疗方案。西安交通大学第一附属医院应用改良MINE方案治疗3例继发于侵袭性NK细胞白血病和T细胞淋巴瘤的噬血细胞综合征患者,初步显示该方案对NK/T细胞淋巴瘤的疗效以及对继发噬血细胞综合征炎症状态的控制和良好的耐受性。
Lymphoma-associated hemophagocytic syndrome is aggressive with rapid progression,particularly in NK/T cell lymphoma.The MINE regimen is a salvage treatment for aggressive non-Hodgkin lymphoma.In our center,the modified MINE regimen was applied to treat three patients with hemophagocytic syndrome secondary to aggressive NK cell leukemia and T-cell lymphoma.The modified MINE regimen showed good efficacy against NK/T cell lymphoma,control of the inflammatory state of secondary hemophagocytic syndrome,and good tolerability.
作者
吴迪
李淼静
李瑶
逯彤霞
付璐瑶
贺鹏程
Wu Di;Li Miaojing;Li Yao;Lu Tongxia;Fu Luyao;He Pengcheng(Department of Hematology,the First Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710061,China;Department of Hematology and Oncology,Nuclear Industry 417 Hospital,Xi'an 710600,China)
出处
《中华血液学杂志》
CAS
CSCD
北大核心
2024年第6期599-601,共3页
Chinese Journal of Hematology
基金
陕西省重点研发计划项目资助(2022SF-008)。
