摘要
目的:分析小儿豉翘清热颗粒配合阿莫西林钠克拉维酸钾治疗急性化脓性扁桃体炎的效果。方法:选择2023年1—12月鄂州二医院收治的86例急性化脓性扁桃体炎患儿作为研究对象。随机分为对照组、试验组,各43例。对照组予以阿莫西林钠克拉维酸钾治疗,试验组在对照组基础上辅以小儿豉翘清热颗粒治疗,两组均治疗7 d。比较两组的临床疗效、症状改善时间、T淋巴细胞亚群水平及用药安全性。结果:试验组治疗总有效率为95.35%,明显高于对照组的81.40%,差异有统计学意义(P<0.05)。试验组发热、咽痛、扁桃体肿大、脓性分泌物改善时间明显短于对照组,差异有统计学意义(P<0.05)。治疗后,试验组CD3^(+)、CD4^(+)水平高于治疗前及对照组,CD8^(+)水平低于治疗前及对照组,差异有统计学意义(P<0.05)。两组不良反应总发生率比较,差异无统计学意义(P>0.05)。结论:急性化脓性扁桃体炎患儿接受小儿豉翘清热颗粒配合阿莫西林钠克拉维酸钾治疗,可起到显著增效作用,能促进患儿症状恢复,改善患儿免疫功能,且安全性良好。
Objective:To analyze the effect of Xiao’er Chiqiao Qingre Granules combined with Amoxicillin Sodium and Clavulanate Potassium in the treatment of acute suppurative tonsillitis.Method:A total of 86 children with acute suppurative tonsillitis treated in E’zhou Second Hospital from January to December 2023 were selected as the study objects.They were randomly divided into control group and experimental group,with 43 cases in each group.The control group was treated with Amoxicillin Sodium and Clavulanate Potassium,and the experimental group was treated with Xiao’er Chiqiao Qingre Granules on the basis of the control group.Both groups were treated for 7 d.The clinical efficacy,symptom improvement time,T lymphocyte subsets and drug safety of the two groups were compared.Result:The total effective rate of the experimental group was 95.35%,which was significantly higher than 81.40%of the control group,the difference was statistically significant(P<0.05).The improvement time of fever,sore throat,swollen tonsils and purulent secretions in experimental group were significantly shorter than those in control group,and the differences were statistically significant(P<0.05).After treatment,the levels of CD3^(+) and CD4^(+) in experimental group were higher than those before treatment and in control group,and the levels of CD8^(+) was lower than that before treatment and in control group,the differences were statistically significant(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion:Children with acute suppurative tonsillitis were treated with Xiao’er Chiqiao Qingre Granules combined with Amoxicillin Sodium and Clavulanate Potassium,which can play a significant synergistic effect,promote the recovery of symptoms and improve the immune function of children with good safety.
作者
包凤君
包中文
BAO Fengjun;BAO Zhongwen(E’zhou Second Hospital,E’zhou 436000,China;不详)
出处
《中外医学研究》
2024年第19期130-134,共5页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
急性化脓性扁桃体炎
抗感染药
中药制剂
T
淋巴细胞
Acute suppurative tonsillitis
Anti-infective drugs
Traditional Chinese medicine preparations
T lymphocytes
