摘要
针灸在减轻化疗药物不良反应方面的应用已经得到国内外的广泛认可,而对于其协同化疗增加抗肿瘤疗效的效应及其机制则较少进行归纳总结。本文对近几年针灸联合化疗增效的临床及基础研究进行回顾,结果显示针灸可一定程度协同化疗抑瘤,并改善患者生存质量;其效应机制与针灸联合化疗药物可促进肿瘤细胞凋亡、改善肿瘤免疫及血管微环境、促进肿瘤局部化疗药富集等有关。本文为针灸作为提高化疗疗效的辅助疗法提供证据和研究思路。
The application of acupuncture and moxibustion in alleviating the adverse effects of chemotherapy drugs has been widely recognized at home and abroad,but the studies have been rarely summarized for the enhanced anti-tumor effect and its mechanism of acupuncture and moxibustion to synergize the chemotherapy drugs.This paper reviewed the clinical and basic studies on the synergism of chemotherapy with acupuncture and moxibustion in recent years.It was found that chemotherapy synergized with acupuncture and moxibustion can suppress cancer to a certain extent and improve the quality of life in patients.The effect mechanism of acupuncture and moxibustion combined with chemotherapy drugs is related to promoting tumor cell apoptosis,improving the immune and vascular microenvironment,and advancing chemotherapy drug enrichment on the affected area.It provides the evidences and ideas for enhancing the effect of chemotherapy by delivering acupuncture and moxibustion as an adjuvant therapy.
作者
杨元祯
李姗姗
郭义
黄锦
王佳琦
冯怡婷
赵素红
赵文君
徐枝芳
YANG Yuan-zhen;LI Shan-shan;GUO Yi;HUANG Jin;WANG Jia-qi;FENG Yi-ting;ZHAO Su-hong;ZHAO Wenjun;XU Zhi-fang(Research Center of Experimental Acupuncture Science,Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China;College of Traditional Chinese Medicine,Tianjin University of Traditional Chinese Medicine,Tianjin 301617;Graduate School of Humanities and Social Sciences,Saitama University,Saitama Prefecture 330-9301,Japan;College of Acupuncture-moxibustion and Tuina,Tianjin University of Traditional Chinese Medicine,Tianjin 301617)
出处
《针刺研究》
CAS
CSCD
北大核心
2024年第6期634-640,共7页
Acupuncture Research
基金
国家自然科学基金重点项目(No.82030125)
天津市大学生创新创业训练计划项目(No.202210063035)。
关键词
针灸
肿瘤
化疗
增效
Acupuncture and moxibustion
Tumor
Chemotherapy
Synergism
