摘要
目的分析神经母细胞瘤术前诊断及根治术后疗效评估中CT检查的应用价值。方法回顾性分析2020年2月至2024年2月安徽医科大学附属省儿童医院收治的疑似神经母细胞瘤患儿80例资料,依据美国儿童肿瘤学会(COG)分级系统分为高危组(25例)、中危组(25例)、低危组(30例)三组。分析CT对神经母细胞瘤的诊断价值,统计分析三组术前CT表现和术后临床疗效。结果80例患儿行CT检查和手术病理检查,对神经母细胞瘤的检出率分别为92.50%(74/80)和100.00%(80/80),差异无统计学意义(P<0.05),其中CT检查有4例误诊为肾母细胞瘤,2例误诊为肝母细胞瘤。肿瘤最长径在低危、中危和高危组之间存在明显差异(P<0.05),且随着风险等级的增加,肿瘤最长径呈现增加的趋势;占位效应在低危、中危和高危组之间存在明显差异(P<0.05),且随着风险等级的增加,占位效应的发生率呈现下降的趋势;外侵表现在低危、中危和高危组之间存在明显差异(P<0.05),且随着风险等级的增加,外侵表现的发生率呈现上升的趋势(P<0.05)。结论神经母细胞瘤术前诊断及根治术后疗效评估中CT检查的应用价值较高。
Objective To analyze the application value of CT examination in preoperative diagnosis of neuroblastoma and evaluation of curative effect after radical treatment.Methods 80 children with neuroblastoma in our hospital from February 2020 to February 2024 were retrospectively selected and divided into the high-risk group(25 cases),the medium-risk group(25 cases),and the low-risk group(30 cases)according to the COG grading system.The diagnostic value of CT in neuroblastoma was analyzed,and the preoperative CT findings and postoperative clinical efficacy of the three groups were statistically analyzed.Results 80 children underwent CT examination and surgical pathological examination,and the detection rates of neuroblastoma were 92.50%(74/80)and 100.00%(80/80),respectively,with no statistically significant difference(P<0.05).Among them,4 cases were misdiagnosed as nephroblastoma and 2 cases were misdiagnosed as hepatoblastoma on CT examination.The longest tumor diameter was significantly different among low-risk,medium-risk and high-risk groups(P<0.05),and with the increase of risk grade,the longest tumor diameter showed an increasing trend.There were significant differences between low-risk,medium-risk,and high-risk groups on the space-occupying effect(P<0.05),and with the increase of risk grade,the incidence of space-occupying effect showed a decreasing trend.There were significant differences among low-risk,medium-risk and high-risk groups on the incidence of invasion(P<0.05),and the incidence of invasion showed an increasing trend with the increase of risk grade(P<0.05).Conclusion CT examination is of high value in preoperative diagnosis of neuroblastoma and evaluation of curative effect after radical treatment.
作者
芮刚
高群
卢贤映
赛恺
潮敏
RUI Gang;GAO Qun;LU Xianying;SAI Kai;CHAO Min(Department of Surgical Oncology,Provincial Children's Hospital Affiliated to Anhui Medical University,Hefei 230051,China;Department of Surgical Oncology,the Fifth Clinical College of Anhui Medical University,Hefei 230051,China;Department of Oncology,Anhui Children's Hospital,Hefei 230051,China)
出处
《中华灾害救援医学》
2024年第3期312-315,共4页
Chinese Journal of Disaster Medicine
