摘要
1例22岁男性患者因腹痛、腹泻自行口服藿香正气水10 mL,bid,当天症状明显缓解。次日上午、下午及第3日上午分别口服藿香正气水10 mL,约30 min后均出现心悸发作,可自行缓解。查心电图示多种心律失常交替,包括紊乱性房性心律、阵发性心房颤动、阵发性室上性心动过速、频发性室性期前收缩、交界性期前收缩、房室传导阻滞及窦性心动过缓。入院后予心电监护,极化液、维拉帕米注射液等对症治疗症状缓解,治疗12 d后病情改善,心电图示窦性心律。该病例提示藿香正气水作为非处方药,用药安全更应受到临床与公众的关注。患者使用藿香正气水期间如出现心悸症状,应警惕严重心律失常的可能,及时就医并治疗。
A 22-year-old male self-administered Huoxiang Zhengqi liquid(10 mL,bid)orally due to abdominal pain and diarrhea.The symptoms improved significantly on the same day.Palpitations occurred about 30 minutes after 10 mL Huoxiang Zhengqi Liuquid administration in the morning and afternoon of the next day and in the morning of the third day,respectively,which was spontaneously relieved.Electrocardiogram showed that multiple arrhythmias alternated,including disordered atrial rhythm,paroxysmal atrial fibrillation,paroxysmal supraventricular tachycardia,frequent premature ventricular contractions,junctional premature contractions,atrioventricular block,and sinus bradycardia.After admission,the patient was given electrocardiography monitoring,polarizing fluid,verapamil injection,and other treatment methods to relieve symptoms,after 12 days of treatment,the patient's condition improved,and the electrocardiogram showed sinus rhythm.This case suggests that as an over-the-counter drug,the safety of Huoxiang Zhengqi liquid should be paid more attention by clinic and public.If patients manifest palpitation symptoms while using Huoxiang Zhengqi liquid,it is imperative to consider the potential for drug-induced serious arrhythmia and get medical treatment promptly.
作者
赵银萍
辛小宇
谢贵波
李华燕
晏媛
ZHAO Yinping;XIN Xiaoyu;XIE Guibo;LI Huayan;YAN Yuan(Department of Pharmacy,Nanfang Hospital Zengcheng Campus,Southern Medical University,Guangzhou 511300,China;Department of Cardiology,Nanfang Hospital Zengcheng Campus,Southern Medical University,Guangzhou 511300,China)
出处
《药物流行病学杂志》
CAS
2024年第4期476-480,共5页
Chinese Journal of Pharmacoepidemiology
关键词
藿香正气水
心律失常
药品不良反应
Huoxiang Zhengqi liquid
Cardiac arhythmia
Adverse drug reactions
