摘要
糖尿病足溃疡常导致难愈性慢性创面,传统的纱布等敷料难以满足当前临床治疗的需求。新型“药辅合一”中药凝胶具备了治疗和敷料的双重特性,具有抗炎、抗溃疡和伤口修复等药理活性,同时能够提供创面修复所需要的湿润环境,有较好的伤口包裹性及优秀的生物相容性和低毒性,从而更好地满足临床需求。本文就常见的“药辅合一”中药凝胶在创面愈合方面的研究进展进行综述,为糖尿病足溃疡的治疗及后续功能性敷料的开发研究提供基础。
Diabetic foot ulcers often lead to refractory chronic wounds,and traditional dressings such as gauze are difficult to meet the needs of current clinical treatment.The new“unifying medicines and excipient”traditional Chinese medicine gel has the dual characteristics of treatment and dressing,with pharmacological activities such as anti-inflammatory,anti-ulcer,and wound repair,and can provide a moist environment required for wound repair,with better wound wrapping,excellent biocompatibility,and low toxicity,so as to better meet clinical needs.This article reviews the research progress of traditional Chinese medicine gel with dual characteristics of“unifying medicines and excipient”in wound healing,which provides a basis for the treatment of diabetic foot ulcer and the development of subsequent functional dressings.
作者
胡雨欣
胡万萱
赵杰
HU Yuxin;HU Wanxuan;ZHAO Jie(Department of Traditional Chinese Medicine,the First Affiliated Hospital of Anhui Medical University,Anhui Province,Hefei 230000,China;Department of Burns,the First Affiliated Hospital of Anhui Medical University,Anhui Province,Hefei 230000,China)
出处
《中国医药导报》
CAS
2024年第7期36-39,共4页
China Medical Herald
基金
国家自然科学基金青年科学基金资助项目(81903994)。
关键词
中药凝胶
药辅合一
敷料
糖尿病足溃疡
慢性创面
综述
Traditional Chinese medicine gel
Unifying medicines and excipient
Wound dressing
Diabetic foot ulcer
Chronic wound
Review
