摘要
目的 比较血管内介入治疗与显微镜下开颅手术夹闭针对颅内动脉瘤患者的治疗效果差异。方法 回顾性选取2020年6月—2023年5月山东大学济阳区人民医院收治的97例颅内动脉瘤患者的临床资料,根据治疗方式的不同分为两组,对照组(n=48)采用显微镜下开颅手术夹闭治疗,观察组(n=49)实施血管内介入治疗,比较两组患者的临床疗效。结果 观察组治疗总有效率(95.92%)高于对照组(79.17%),差异有统计学意义(χ^(2)=6.276,P=0.012)。观察组术后3个月的血管假性血友病因子、内皮素-1水平低于对照组,一氧化氮水平均高于对照组,差异有统计学意义(P均<0.05)。观察组术中出血量少于对照组,观察组手术时间、住院时间均短于对照组,差异有统计学意义(P均<0.05)。结论 在开展对颅内动脉瘤的治疗中,血管内介入治疗比显微镜下开颅手术夹闭效果更显著,可明显改善患者的血管内皮功能。
Objective To compare the difference in treatment effect between endovascular intervention and microscopic craniotomy clamping for patients with intracranial aneurysms.Methods The clinical data of 97 patients with intracranial aneurysms admitted to Jiyang District People's Hospital in Jinan City from June 2020 to May 2023 were retrospectively selected and divided into two groups based on different treatment methods.The control group(n=48) received microscopic craniotomy clamping treatment,while the observation group(n=49) received endovascular intervention treatment.The clinical efficacy of the two groups of patients was compared.Results The total effective rate of treatment in the observation group(95.92%) was higher than that in the control group(79.17%),and the difference was statistically significant(χ^(2)=6.276,P=0.012).The levels of von Willebrand factor and endothelin-1 were lower and nitric oxide was significantly higher in the observation group compared to the control group at 3 months postoperatively,and the differences were statistically significant(all P<0.05).The intraoperative bleeding of the observation group was less than that of the control group,and the operation time and hospitalization time of the observation group were shorter than those of the control group,and the differences were statistically significant(both P<0.05).Conclusion In carrying out the treatment of intracranial aneurysm,the effect of endovascular interventional therapy is more significant than microscopic craniotomy clamping,and the patient's vascular endothelial function is significantly improved.
作者
高磊
郑玉梅
GAO Lei;ZHENG Yumei(Department of Neurosurgery,Jinan Jiyang District People's Hospital,Jinan,Shandong Province,251400 China;Outpatient Nursing Department,Jinan Jiyang District People's Hospital,Jinan,Shandong Province,251400 China)
出处
《系统医学》
2024年第4期141-143,147,共4页
Systems Medicine
关键词
颅内动脉瘤
血管内介入治疗
显微镜下开颅手术夹闭
治疗效果
Intracranial aneurysm
Endovascular interventional therapy
Microscopic craniotomy
Therapeutic effect
