摘要
目的观察推拿治疗小儿急性化脓性扁桃体炎的临床疗效及对免疫功能的调节。方法选取2020年1月—2022年12月乌兰浩特市扎赉特旗人民医院收治的80例急性化脓性扁桃体炎住院患儿,按随机数字表法分为观察组(40例)与对照组(40例),实际观察组39例(失访1例),对照组38例(失访1例、主动退出1例)。对照组给予头孢呋辛钠加对症支持治疗,观察组在对照组基础上加用小儿推拿治疗,两组均治疗7 d。比较两组临床疗效、临床症状消退时间以及炎症指标[白细胞计数(WBC)、血清C反应蛋白(CRP)]、免疫因子[白细胞介素-4(IL-4)、γ-干扰素(IFN-γ)]水平的变化。结果观察组临床疗效总有效率为94.87%,对照组为89.47%,两组比较,差异无统计学意义(P>0.05)。治疗后,观察组临床症状缓解时间均明显少于对照组,差异有统计学意义(P<0.01)。治疗后,两组WBC、CRP、IL-4水平均较治疗前下降,且观察组上述3项水平均低于对照组,差异均有统计学意义(P<0.05,P<0.01);两组IFN-γ水平较治疗前升高,且观察组水平高于对照组,差异有统计学意义(P<0.05,P<0.01)。结论小儿推拿治疗急性化脓性扁桃体炎可明显改善患儿临床症状,减轻炎症反应,调节患儿的Th1/Th2免疫应答,疗效显著,值得临床推广应用。
Objective To observe the clinical efficacy of tuina therapy for acute suppurative tonsillitis in children and its regulation of immune function.Methods This paper selected 80 hospitalized children with acute suppurative tonsillitis admitted to Zhalaite Banner People's Hospital in Ulanhot City from January 2020 to December 2022 and divided them into an observation group(40 cases)and a control group(40 cases)by using a random number table method.There were 39 cases in the actual observation group(one case was lack of follow-up)and 38 cases in the control group(one case was lack of follow-up,and one case had voluntary withdrawal).The control group received symptomatic supportive treatment with cefuroxime sodium,while the observation group received tuina therapy on the basis of the control group.Both groups were treated for seven days.The changes in clinical efficacy,relief time of clinical symptoms,inflammatory markers[white blood cell count(WBC)and serum C-reactive protein(CRP)],and immune factors[interleukin-4(IL-4)andγ-Interferon(IFN-γ)]between the two groups were compared.Results The total effective rate of clinical efficacy in the observation group was 94.87%,while in the control group,it was 89.47%.There was no statistically significant difference between the two groups(P>0.05).After treatment,the relief time of clinical symptoms in the observation group was significantly shorter than that in the control group,and the difference was statistically significant(P<0.01).After treatment,the levels of WBC,CRP,and IL-4 in both groups decreased,and those in the observation group were lower than those in the control group,with a statistically significant difference(P<0.05,P<0.01).The IFN-γlevel in both groups increased after treatment,and the observation group had a higher level than the control group,with a statistically significant difference(P<0.05,P<0.01).Conclusion Tuina therapy for acute suppurative tonsillitis in Children can significantly improve clinical symptoms,alleviate inflammatory reactions,and regulate Th1/Th2 immune responses in children,with significant therapeutic effects.It is worthy of clinical promotion and application.
作者
王静
WANG Jing(Fengtai District Maternal and Child Health Hospital of Beijing Municipality Pediatrics,Beijing 100067,China)
出处
《基层中医药》
2024年第3期35-40,共6页
Basic Traditional Chinese Medicine
基金
北京市中医妇幼名医传承工作室建设项目
丰台区卫生健康系统科研项目(2020-46)
国家中医药管理局第四批全国中医(临床、基础)优秀人才研修项目(国中医药办人教函〔2017〕124号)。
关键词
急性化脓性扁桃体炎
儿童
推拿
免疫功能
acute suppurative tonsillitis
children
tuina
immune function
