摘要
器官移植后,移植物的排斥反应是最常见的并发症之一,无论病因如何都会对移植物产生不良损害。三级淋巴结构(TLS)于病理情况下非淋巴组织内发生。针对调节移植物排斥反应的机制鉴定和表征,不仅能够促进人们对器官移植物的存活及预后的理解,而且还为治疗移植物排斥反应提供了思路。
s:After organ transplantation,graft rejection is one of the most common complications,which will cause adverse injuries to grafts regardless of etiology.Tertiary lymphoid structures(TLS)occur in non-lymphoid tissues under pathological conditions.Identification and characterization of mechanisms regulating graft rejection can not only promote understanding of the survival and prognosis of organ grafts,but also provide ideas for treating graft rejection reaction.
作者
杨麒臻
王英
陈乾
牛玉林
YANG Qizhen;WANG Ying;CHEN Qian;NIU Yulin(Department of Organ Transplantation,the Affiliated Hospital of Guizhou Medical University,Guiyang,Guizhou,550000;Department of Neurology,the Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine,Guiyang,Guizhou,550000)
出处
《实用临床医药杂志》
CAS
2024年第5期144-148,共5页
Journal of Clinical Medicine in Practice
基金
2023年贵州省基础研究计划(自然学科类)项目[黔科合基础-ZK(2023)一般380]。
关键词
三级淋巴结构
器官移植
移植物排斥反应
发病机制
tertiary lymphoid structures
organ transplantation
graft rejection reaction
pathogenesis
