摘要
目的观察电子计算机断层扫描灌注成像(computed tomography perfusion,CTP)辅助血管再通治疗急性缺血性脑卒中(acute ischemic stroke,AIS)的临床效果。方法收集2020年12月—2022年12月淮南新华医院收治的134例AIS患者临床资料,按照治疗方案不同分为观察组(67例)和对照组(67例)。对照组采用常规血管再通治疗方案,观察组在CTP技术辅助下进行血管再通治疗,对比两组血管再通情况和治疗效果。结果治疗后,观察组血管再通良好率为68.66%,高于对照组的43.28%,差异有统计学意义(P<0.05);观察组最小血流量(Qmin)、颈动脉最小血流速度(Vmin)、动态阻抗(dynamic resistance,DR)分别为(4.79±0.48)mL/s、(9.79±0.88)cm/s、(463.92±15.33)Pa·s/m,显著高于对照组的(4.43±0.40)mL/s、(9.34±0.76)cm/s、(420.39±17.3)Pa·s/mL,差异均有统计学意义(P<0.05);观察组格拉斯哥昏迷量表(Glasgow coma scale,GCS)评分高于对照组,美国国立卫生研究院卒中量表(National Institute of Health stroke scale,NIHSS)评分低于对照组,差异有统计学意义(P<0.05);两组患者血管再闭塞、脑水肿等AIS血管再通治疗后常见并发症发生率和3个月死亡率比较,差异无统计学意义(P>0.05)。结论CTP技术辅助血管再通治疗AIS患者,可提高血管再通率,改善患者脑部血液循环,安全性高,疗效确切。
Objective:To observe the clinical effects of electron computed tomography perfusion imaging(CTP)assisted revascularization for acute ischemic stroke(AIS).Methods:Retrospective analysis of the clinical data of 134 patients with AIS admitted to Huainan Xinhua Hospital from December 2020 to December 2022.The patients were divided into the study group(67 cases)and the control group(67 cases)in terms of the treatment regimen.The control group was treated with conventional revascularization regimen.The observation group underwent revascularization with the assistance of CTP technique.The revascularization and treatment results of the two groups were compared.Results:After treatment,the good rate of vascular reperfusion in the study group was 68.66%,which was higher than that in the control group(43.28%;P<0.05).The minimum blood flow(Qmin),minimum carotid blood flow velocity(Vmin),and dynamic resistance(DR)in the study group were(4.79±0.48)mL/s,(9.79±0.88)cm/s,and(463.92±15.33)Pa·s/m,respectively,which were significantly higher than those in the control group(4.43±0.40)mL/s,(9.34±0.76)cm/s,and(420.39±17.3)Pa·s/mL(P<0.05).The Glasgow Coma Scale(GCS)score in the study group was higher than that in the control group,while the National Institutes of Health Stroke Scale(NIHSS)score was lower(P<0.05).There was no significant difference in the incidence of common complications such as vascular reocclusion and cerebral edema after reperfusion therapy for AIS and 3-month mortality between the two groups(P>0.05).Conclusion:To apply CTP technology assisted revascularization therapy to the treatment of patients with AIS can increase the rate of revascularization and improve blood circulation in the brain of patients,which is safe and effective.
作者
刘丽娜
石英娜
孙伟
LIU Lina;SHI Yingna;SUN Wei(Huainan Vocational and Technical College Medical School,Huainan 232001,China;Imaging Department,Huainan Xinhua Hospital,Huainan 232052,China;CT Room,Huainan Xinhua Hospital,Huainan 232052,China)
出处
《山东第一医科大学（山东省医学科学院）学报》
CAS
2024年第2期90-93,共4页
Journal of Shandong First Medical University ＆ Shandong Academy of Medical Sciences
关键词
急性缺血性脑卒中
脑灌注成像技术
血管再通
溶栓治疗
预后
acute ischemic stroke
computed tomography perfusion imaging
revascularization
thrombolytic treatment
prognosis
