摘要
目的:分析腹腔镜下卵巢囊肿剥除术对卵巢良性肿瘤患者炎性水平、卵巢及免疫功能的影响。方法:回顾性分析2019年6月~2022年6月本院72例卵巢良性肿瘤患者的临床资料,按照手术方法分组。对照组采用开腹卵巢囊肿剥除术,观察组采用腹腔镜下卵巢囊肿剥除术,对比两组炎性水平、卵巢及免疫功能指标。结果:术前1d,两组TNF-α、CRP对比,无显著差异(P>0.05);术后24h,观察组TNF-α、CRP水平低于对照组(P<0.05)。术前1d,两组免疫功能指标无显著差异(P>0.05);术后24h,观察组CD3^(+)、CD4^(+)、CD4^(+)/CD8^(+)与对照组对比,数据差异显著(P<0.05),两组CD8^(+)对比无显著差异(P>0.05)。术后3个月,观察组FSH、LH水平低于对照组,E2水平高于对照组(P<0.05)。结论:卵巢良性肿瘤患者接受腹腔镜下卵巢囊肿剥除术治疗,术后炎性反应小,卵巢及免疫功能好。
Objective:To analyze the effects of laparoscopic ovarian cyst excision on inflammatory level,ovarian and immune function in patients with benign ovarian tumors.Methods:Clinical data of 72 patients with benign ovarian tumor in our hospital from June 2019 to June 2022 were retrospectively analyzed,and grouped according to surgical methods.Control group:laparotomy ovarian cyst excision,observation group:laparoscopic ovarian cyst excision,the inflammatory level,ovarian and immune function indexes of the two groups were compared.Results:1 day before surgery,there were no significant differences in TNF-α(tumor necrosis factor-α)and CRP(C-reactive protein)between two groups(P>0.05).24h after operation,the levels of TNF-αand CRP in observation group were lower than those in control group(P<0.05).1 day before surgery,there were no significant differences in immune function indexes between the two groups(P>0.05).24h after surgery,CD3^(+),CD4^(+),CD4^(+)/CD8^(+)in the observation group were significantly compared with the control group(P<0.05),but there was no significant difference in CD8^(+)between the two groups(P>0.05).3 months after surgery,FSH(follicle stimulating hormone)and LH(luteinizing hormone)levels in the observation group were lower than those in the control group,and E2(estradiol)levels were higher than those in the control group(P<0.05).Conclusion:The patients with benign ovarian tumor were treated with laparoscopic ovarian cyst excision,and the postoperative inflammatory reaction was small,and the ovarian and immune function were good.
作者
熊艳
XIONG Yan(Yongxiu County People’s Hospital,Jiangxi Jiujiang 330304)
出处
《中国医疗器械信息》
2024年第4期42-44,共3页
China Medical Device Information
关键词
腹腔镜
卵巢囊肿剥除术
炎症
免疫功能
卵巢功能
laparoscope
excision of ovarian cyst
inflammation
immunity
ovarian function
