摘要
目的:探究腹部提压心肺复苏对心脏骤停患者血流动力学、脑功能、心肌酶的影响。方法:选取2021年1月—2023年1月新余市人民医院收治心脏骤停患者94例,以随机数字表法将其分为对照组(常规心肺复苏)及观察组(腹部提压心肺复苏技术)各47例,对比两组血流动力学[心率(HR)、平均动脉压(MAP)、中心静脉压(CVP)]、脑功能[神经元特异性烯醇化酶(NSE)、S100蛋白(S100β)、脑源性神经营养因子(BDNF)]、心肌酶谱指标[心肌肌钙蛋白(cTnI)、乳酸脱氢酶(LDH)、肌酸激酶(CK)]、氧代谢指标[颈内静脉血氧饱和度(SjvO_(2))、动脉-颈内静脉血氧含量差(Ca-jvO_(2))、脑氧摄取率(ERO_(2))]、并发症发生率。结果:复苏20 min后,观察组HR、MAP、CVP水平均高于对照组(P<0.05)。复苏1 h后,对照组NSE、S100β水平均高于观察组,BDNF低于观察组(P<0.05)。复苏1 h后,观察组cTnI、LDH、CK水平均低于对照组(P<0.05)。复苏24 h后,对照组SjvO_(2)、Ca-jvO_(2)、ERO_(2)水平均低于观察组(P<0.05)。观察组并发症发生率低于对照组(P<0.05)。结论:对心脏骤停患者进行腹部提压心肺复苏,可改善患者血流动力学,保护患者脑功能,减轻心肌损伤,降低并发症发生率。
Objective:To investigate the effects of abdominal compression cardiopulmonary resuscitation on hemodynamics,brain function and cardiac enzymes in patients with cardiac arrest.Method:Ninety-four patients with cardiac arrest admitted to Xinyu People's Hospital from January 2021 to January 2023 were selected and divided into the control group(conventional cardiopulmonary resuscitation) and the observation group(abdominal compressional cardiopulmonary resuscitation technique) of 47 cases each by random number table method.The hemodynamics [heart rate(HR),mean arterial pressure(MAP),central venous pressure(CVP)],brain function [neuron-specific enolase(NSE),S100 protein(S100β),brain-derived neurotrophic factor(BDNF)],myocardial enzyme spectrum indexes [cardiac troponin(cTnI),lactate dehydrogenase(LDH),creatine kinase(CK)],oxygen metabolism indexes [internal jugular venous oxygen saturation(SjvO_(2)),arterial-internal jugular vein oxygen difference(Ca-jvO_(2)),cerebral oxygen extraction rate(ERO_(2))] and complications were compared between the two groups.Result:After 20 minutes of resuscitation,HR,MAP and CVP levels in the observation group were higher than those in the control group(P<0.05).After 1 hour of resuscitation,the levels of NSE and S100β in the control group were higher than those in the observation group,and BDNF was lower than that in the observation group(P<0.05).After 1 hour of resuscitation,the levels of cTnI,LDH and CK in the observation group were lower than those in the control group(P<0.05).After 24 hours of resuscitation,SjvO_(2),Ca-jvO_(2) and ERO_(2) levels in the control group were lower than those in the observation group(P<0.05).The rate of complication in the observation group was lower than that in the control group(P<0.05).Conclusion:Performing abdominal compression cardiopulmonary resuscitation on patients in cardiac arrest can improve patients' hemodynamics,protect their brain function,reduce myocardial injury and decrease the incidence of complications.
作者
郭云
艾青涯
阮军平
沈锦明
廖彧
GUO Yun;AI Qingya;RUAN Junping;SHEN Jinming;LIAO Yu(Department of Emergency,Xinyu People's Hospital,Xinyu 338000,China;不详)
出处
《中国医学创新》
CAS
2024年第3期22-26,共5页
Medical Innovation of China
基金
新余市指导性科技计划项目(20223090861)。
关键词
腹部提压心肺复苏
心脏骤停
血流动力学
脑功能
心肌酶
Abdominal compression cardiopulmonary resuscitation
Cardiac arrest
Haemodynamics
Cerebral function
Cardiac enzymes
