摘要
目的:探讨动态增强MRI(DCE-MRI)定量参数鉴别诊断泪腺IgG4相关性病变(IgG4-RLD)、淋巴瘤、炎性假瘤的价值。方法:搜集2010年9月至2021年12月间经病理证实的泪腺IgG4-RLD、淋巴瘤及炎性假瘤患者的病例资料;比较泪腺IgG4-RLD组、淋巴瘤组、炎性假瘤组的DCE-MRI定量参数(K^(trans)、K_(ep)、V_(e))差异,采用ROC曲线分析上述参数对IgG4-RLD的诊断效能。结果:泪腺淋巴瘤的V_(e)值(0.43±0.21)低于泪腺IgG4-RLD(0.68±0.20)和炎性假瘤(0.74±0.23),差异均有统计学意义(P均<0.05);泪腺IgG4-RLD与炎性假瘤的V_(e)值差异无统计学意义(P=0.397)。泪腺IgG4-RLD、炎性假瘤、淋巴瘤的K^(trans)、K_(ep)差异均无统计学意义(P均>0.05)。K^(trans)、K_(ep)、V_(e)及三参数联合诊断泪腺IgG4-RLD的效能(AUC)分别为0.545、0.540、0.545、0.620,差异均无统计学意义(P均>0.05)。结论:V_(e)有助于泪腺IgG4-RLD、淋巴瘤、炎性假瘤的鉴别;DCE-MRI定量参数对于泪腺IgG4-RLD的诊断有一定临床价值。
Objective:To explore the efficiency of the quantitative parameters of Dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI)in the differential diagnosis of Immune globulin G4-related lacrimal disease(IgG4-RLD)from lymphoma and inflammatory pseudotumor.Methods:The data of patients with IgG4-RLD,lymphoma and inflammatory pseudotumor from September 2010 to December 2021 were acquired.The quantitative parameters of DCE-MRI including K^(trans),K_(ep),and V_(e) were compared among the three groups and the diagnostic efficacy of IgG4-RLD was predicted by ROC curve.Results:The V_(e) value of lymphoma(0.43±0.21)was lower than that of IgG4-RLD(0.68±0.20)and inflammatory pseudotumor(0.74±0.23),and the differences were statistically significant(P<0.05).The V_(e) value was not significantly different between IgG4-RLD and inflammatory pseudotumor(P=0.397).The K^(trans) and K_(ep) values were not significantly different among groups(P>0.05).The accuracy were 0.545,0.540,0.545,and 0.620 using K^(trans),K_(ep),V_(e),and combined there three parameters,respectively and were not significantly different(P>0.05).Conclusions:The V_(e) value contributes to the differential diagnosis among IgG4-RLD,lymphoma,and inflammatory pseudotumor.The quantitative parameters of the DCE-MRI is value for the diagnosis of IgG4-RLD.
作者
李靖
云雨婷
王紫仪
付琳
马建民
杨本涛
Li Jing;Yun Yu-ting;Wang Zi-yi(Department of Radiology,the Fourth Hospital of Changsha,Hunan 410006,China)
出处
《放射学实践》
CSCD
北大核心
2024年第1期65-69,共5页
Radiologic Practice
关键词
磁共振成像
泪腺
IgG4相关性病变
淋巴瘤
炎性假瘤
Magnetic resonance imaging
lacrimal gland
immunoglobulin G4-related disease
lymphoma
inflammatory pseudotumor
