摘要
目的研究子宫动脉血流频谱异常高危孕妇应用小剂量阿司匹林对子痫前期的预防价值,以降低高危孕妇围生儿死亡。方法选取200例子宫动脉血流频谱异常高危孕妇,按照孕妇就诊序号奇偶数进行分组,奇数列入试验组,偶数列入对照组,每组100例。试验组孕妇进行小剂量阿司匹林预防性治疗,对照组常规监测。比较两组子痫前期及重度子痫前期发病率及妊娠结局。结果试验组治疗后子痫前期发病率为1.00%,重度子痫前期发病率为0;对照组子痫前期发病率为7.00%,重度子痫前期发病率为4.00%。试验组子痫前期发病率、重度子痫前期发病率均显著低于对照组,差异具有统计学意义(P<0.05)。试验组治疗后早产率、产后出血率均明显低于对照组,差异有统计学意义(P<0.05)。结论对于子宫动脉血流频谱异常高危孕妇口服小剂量阿司匹林可有效预防子痫前期的发生,也能降低孕产妇死亡率及围生儿死亡率。
Objective To study the preventive value of low-dose aspirin for preeclampsia in high-risk pregnant women with abnormal uterine artery flow spectrum in order to reduce perinatal death.Methods 200 pregnant women at high risk of abnormal uterine artery flow spectrum were selected and divided into groups according to odd and even serial number of pregnant women.Odd numbers were included in the test group and even numbers were included in the control group,with 100 cases in each group.The pregnant women in the experimental group received low-dose aspirin prophylactic treatment,and the control group received routine monitoring.The incidence and pregnancy outcome of preeclampsia and severe preeclampsia were compared between the two groups.Results The incidence of preeclampsia after treatment was 1.00%and the incidence of severe preeclampsia was 0.In the control group,the incidence of preeclampsia was 7.00%and the incidence of severe preeclampsia was 4.00%.The incidence of preeclampsia and severe preeclampsia in experimental groups were significantly lower than those in control group,with statistical significance(P<0.05).The preterm birth rate and postpartum hemorrhage rate of the experimental group were significantly lower than those of the control group,and the differences were statistically significant(P<0.05).Conclusion For high-risk pregnant women with abnormal uterine artery flow spectrum,oral low-dose aspirin can effectively prevent the occurrence of preeclampsia,and also reduce maternal mortality and perinatal mortality.
作者
张月梅
周宏霞
Zhang Yuemei;Zhou Hongxia(Perinatal Medicine Center,Baoying Maternal and Child Health Hospital,Yangzhou 225800,China)
出处
《实用妇科内分泌电子杂志》
2023年第25期53-55,共3页
Electronic Journal of Practical Gynecological Endocrinology
基金
江苏省妇幼健康科研项目(编号F202142)。
关键词
子痫前期
高危孕妇
阿司匹林
小剂量
预防效果
Preeclampsia
High-risk pregnant women
Aspirin
Small doses
Preventive effect
