摘要
目的对比分析急性阑尾炎患者的临床治疗采用腹腔镜手术、开腹手术的具体方式及临床疗效。方法随机选取2021年3月—2022年10月期间山东大学第七人民医院急诊科收治的80例急性阑尾炎患者为研究对象,应用单双号分组的方式分为两组,每组40例。对照组接受开腹手术治疗,研究组接受腹腔镜手术治疗,比较两组手术相关指标、免疫应激指标、术后不同阶段疼痛指标以及并发症发生率。结果研究组手术时间、术中出血量、住院时间、肛门排气时间、下床活动时间、进食时间均优于对照组,差异有统计学意义(P<0.05)。术后3 d,研究组免疫球蛋白G、免疫球蛋白M、前清蛋白均高于对照组,差异有统计学意义(P<0.05)。术后3 d,研究组白细胞介素-6(51.01±1.03)ng/L、C反应蛋白(55.45±1.34)mg/L、肿瘤坏死因子-α(21.78±1.42)ng/L均低于对照组的(57.15±1.17)ng/L、(61.03±1.32)mg/L、(26.84±1.55)ng/L,差异有统计学意义(t=24.912、18.762、15.223,P<0.05)。研究组术后不同阶段疼痛评分均低于对照组,差异有统计学意义(P<0.05)。研究组并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论相比开腹手术,腹腔镜手术治疗急性阑尾炎的效果更好。
Objective To compare and analyze the clinical treatment of patients with acute appendicitis by laparoscopic surgery,open surgery and the specific ways and clinical effects.Methods 80 patients with acute appendicitis admitted to the Emergency Department of Jinan Seventh People's Hospital from March 2021 to October 2022 were randomly selected as the research subjects.They were divided into two groups using a single or double number grouping method,with 40 patients in each group.The control group received open surgery treatment,while the study group received laparoscopic surgery treatment.The two groups were compared in terms of surgical related indicators,immune stress indicators,postoperative pain indicators at different stages,and the incidence of complications.Results The operation time,intraoperative blood loss,hospital stay,anal exhaust time,getting out of bed and eating time of the study group were better than those of the control group,and the differences were statistically significant(P<0.05).3 d after surgery,immunoglobulin G,immunoglobulin M and prealbumin in the study group were higher than those in the control group,and the difference was statistically significant(P<0.05).3 d after surgery,the levels of interleukin-6(51.01±1.03)ng/L,C-reactive protein(55.45±1.34)mg/L,tumor necrosis factor-α(21.78±1.42)ng/L in the study group were lower than those in the control group(57.15±1.17)ng/L,(61.03±1.32)mg/L,(26.84±1.55)ng/L,the difference was statistically significant(t=24.912,18.762,15.223,P<0.05).The pain scores of the study group were lower than those of the control group at different stages,and the difference was statistically significant(P<0.05).The complication rate of the study group was lower than that of the control group,and the difference was statistically significant(P<0.05).Conclusion Laparoscopic surgery is more effective than open surgery in the treatment of acute appendicitis.
作者
刘振伟
高兴民
孙明磊
LIU Zhenwei;GAO Xingming;SUN Minglei(Department of Emergency,Jinan Seventh People's Hospital,Jinan,Shandong Province,250000 China)
出处
《中外医疗》
2023年第28期35-38,51,共5页
China & Foreign Medical Treatment