摘要
目的:探究宫腔镜下电切术对子宫黏膜下肌瘤患者子宫内膜容受性及微炎症状态的影响。方法:选取2021年3月—2022年4月泉州东南医院收治的80例子宫黏膜下肌瘤患者。根据随机数表法将其分为对照组和观察组,各40例。对照组采用腹腔镜子宫肌瘤剔除术,观察组采用宫腔镜下电切术。比较两组术中出血量、时间指标,术前、术后1个月子宫内膜容受性,术前、术后3 d微炎症状态。结果:观察组术中出血量少于对照组,首次下床活动时间、术后肛门排气时间均早于对照组,手术时间、住院时间均短于对照组,差异有统计学意义(P<0.05)。术后1个月,两组子宫内膜厚度高于术前,子宫动脉血流阻力指数及搏动指数均低于术前,观察组子宫内膜厚度高于对照组,子宫动脉血流阻力指数及搏动指数均低于对照组,差异有统计学意义(P<0.05)。术后3 d,两组白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、白细胞介素-1β(IL-1β)水平均升高,观察组TNF-α、IL-6、IL-1β水平均低于对照组,差异有统计学意义(P<0.05)。结论:宫腔镜下电切术可改善子宫黏膜下肌瘤患者的子宫内膜容受性,减轻术后微炎症状态,利于患者康复。
Objective:To investigate the effect of hysteroscopic electrotomy on endometrial receptivity and microinflammatory status in patients with uterine submucous myoma.Method:A total of 80 patients with uterine submucous myoma treated in Quanzhou Southeast Hospital from March 2021 to April 2022 were selected.They were divided into control group and observation group according to random number table method,with 40 cases in each group.The control group underwent laparoscopic myomectomy,and the observation group underwent hysteroscopic electrotomy.The amount of intraoperative blood loss,time indexes,endometrial receptivity before and 1 month after surgery,and microinflammatory status before and 3 d after surgery were compared between the two groups.Result:The amount of intraoperative blood loss in the observation group was less than that in the control group,the time of getting out of bed for the first time,the time of postoperative anal exhaust were earlier than those in the control group,and the time of surgery and hospital stay were shorter than those in the control group,the differences were statistically significant(P<0.05).At 1 month after surgery,the endometrial thickness in both groups were higher than before surgery,and the blood flow resistance index and pulse index of uterine artery were lower than before surgery,the endometrial thickness of observation group was higher than that of control group,and the blood flow resistance index and pulse index of uterine artery were lower than those of control group,the differences were statistically significant(P<0.05).At 3 d after surgery,the levels of interleukin-6(IL-6),tumor necrosis factor-α(TNF-α)and interleukin-1β(IL-1β)in both groups were increased,and the levels of TNF-α,IL-6 and IL-1βin the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).Conclusion:Hysteroscopic electrotomy can improve the endometrial receptivity of patients with uterine submucous myoma,relieve postoperative microinflammation staus,and facilitate the rehabilitation of patients.
作者
殷质朴
庄良武
龚博惠
丁丽琴
YIN Zhipu;ZHUANG Liangwu;GONG Bohui;DING Liqin(Quanzhou Southeast Hospital,Quanzhou 362000,China)
出处
《中外医学研究》
2023年第32期42-45,共4页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
子宫黏膜下肌瘤
宫腔镜下电切术
子宫内膜容受性
炎症反应
Uterine submucous myoma
Hysteroscopic electrotomy
Endometrial receptivity
Inflammatory response