摘要
【目的】对中医治疗子宫内膜异位症研究文献中生活质量量表的使用情况进行评价。【方法】检索中文数据库如中国生物医学文献数据库(CMB)、中国知网(CNKI)、维普期刊数据库(VIP)和万方数字化期刊数据库(Wanfang Data)以及英文数据库如PubMed、Embase和CINAHL中有关中医治疗子宫内膜异位症的临床研究文献,对符合要求的文献中的量表应用情况进行分析。量表应用评价从量表选择(是否规范使用量表)、量表使用分析(包括量表维度报告与量表维度分析)、研究设计(是否考虑了混杂因素)和量表参照版本4个方面进行。【结果】共纳入有关中医治疗子宫内膜异位症研究的文献103篇,其中35篇文献选用了专科性量表的子宫内膜异位症生存质量量表EHP-5或EHP-30(合称为EHP-5/30);19篇文献选用了普适性量表的生活质量简表SF-12或SF-36(合称为SF-12/36),另有19篇文献选用了普适性量表的世界卫生组织生存质量测定量表(WHOQOL);12篇文献只说明选用了生存质量量表;10篇文献选用了其他普适性量表;3篇文献选用了妇科专科量表;3篇文献同时选用了2种生存质量量表;2篇文献选用了自制的生存质量量表。纳入分析的文献共涉及9种量表,48篇文献选用了普适性量表,38篇文献选用了专科性量表;使用频率较高的量表为EHP-5/30(35/105,33.98%)、SF-12/36和WHOQOL(均为19/105,18.45%),而其使用规范率则为WHOQOL>SF-12/36>EHP-5/30。涉及的9种量表中,只有2种为国内原创量表,可见于5篇文献中,其余皆为从国外引入的量表。【结论】中医治疗子宫内膜异位症的临床研究中,生活质量量表的选择以国外量表为主,专科性和普适性量表平分秋色,存在量表使用规范情况欠佳、研究者对其重视不足、评价方法不合理等问题。今后的研究需重视生活质量量表的使用及分析的规范性和准确性,以期提升中医药临床研究成果的可信度。
Objective To evaluate the use of quality of life(QOL)scales in the literature on the research of traditional Chinese medicine(TCM)for endometriosis.Methods Clinical research literature on TCM treatment of endometriosis were retrieved from Chinese databases such as CBM,CNKI,VIP and Wanfang Data,and from English databases such as PubMed,Embase,and CINAHL,and then the application of QOL scales in the qualified literature was analyzed.Scale application was evaluated in terms of scale selection(standardized use of the scale or not),scale application analysis(including scale dimension report and scale dimension analysis),study design(consideration of confounding factors or not)and scale reference version.Results A total of 103 articles of TCM treatment for endometriosis were included,of which 35 articles adopted the specialized endometriosis QOL scale of EHP-5 or EHP-30(shortened to the combined term of EHP-5/30)for the evaluation of endometriosis quality of life,19 articles utilized the general scale of the short-form QOL scale of SF-12 or SF-36(shortened to the combined term of SF-12/36),19 articles used the general scale of World Health Organization Quality of Life scale(WHOQOL),12 articles only mentioned the QOL scale,10 articles used other general scales,3 articles chose the gynecology specialist scale,3 articles adopted 2 kinds of QOL scales simultaneously,and 2 articles used the self-developed quality of life scales.A total of 9 scales were included in the analysis,and 48 articles chose general scales while 38 articles used the specialized scales.The frequently-used scales were the EHP-5/30(35/105,33.98%),the SF-12/36(19/105,18.45%)and the WH0Q0L(19/105,18.45%),and the rates for their standardized use in decreasing order were WHOQOL≥>SF-12/36>EHP-5/30.Of the 9 scales involved,only 2 were the original domestic scales which were used in 5 articles,and the rest scales were introduced from abroad.The normative rate was the lowest.Conclusion In the clinical research of TCM therapy for endometriosis,the scales for the evaluation of QOL are mainly introduced from abroad,with the equal proportion in specialized scale and general scale.And there exist the problems such as poor standardization of scale usage,the researchers caring less about the use of QOL scale,and irrational evaluation methods for QOL.More attention should be paid to the standardization and accuracy of the use and analysis of quality of life scales in the future research,so as to enhance the credibility of clinical research results in TCM.
作者
陈艺苑
何思雅
王永霞
梁雪芳
CHEN Yi-Yuan;HE Si-Ya;WANG Yong-Xia;LIANG Xue-Fang(The Second Clinical Medical School of Guangzhou University of Chinese Medicine,Guangzhou 510405 Guangdong,China;Dept.of Gynecology,the Second Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510120 Guangdong,China)
出处
《广州中医药大学学报》
CAS
2023年第12期3196-3206,共11页
Journal of Guangzhou University of Traditional Chinese Medicine
基金
广东省名老中医药专家传承工作室建设项目(国中医药人教函[2018]134号)
广东省中医院刘敏如学术经验传承工作室建设项目(编号:DF02202)。
