摘要
目的探究呼吸窘迫综合征新生儿肠道菌群的改变,为该类患儿的治疗提供参考。方法选取我院2020年4月至2022年4月收治的83例呼吸窘迫综合征新生儿作为试验组,另选我院同期健康新生儿83例作为对照组,收集两组对象粪便标本。对比两组对象肠道菌群的变化情况。结果与对照组相比,试验组患儿肠道菌群Chaol指数和Shannon指数显著降低,Ace指数显著升高,差异均有统计学意义(均P<0.05)。两组对象肠道厚壁菌门、变形菌门、链球菌属相对丰度对比差异均有统计学意义(均P<0.05)。结论呼吸窘迫综合征新生儿肠道菌群改变较大。
Objective To observe the changes of intestinal flora in neonatal respiratory distress syndrome(RDS),providing a reference for the treatment.Methods A total of 83 neonates with RDS admitted in our hospital from April 2020 to April 2022 were selected as the observation group,and 83 healthy neonates in the same period were selected as the control group.Fecal samples of the infants in both groups were collected.The changes of intestinal flora were compared between the two groups.Results The observation group had notably lower Chao1 and Shannon indexes,and higher Ace index than those in control group respectively,with statistical differences(all P<0.05).The relative abundances of Firmicutes,Proteobacteria and Streptococcus in two groups were statistically different(all P<0.05).Conclusion The intestinal flora of neonatal respiratory distress syndrome changed greatly.
作者
王祥诗
余琴
邝少丹
WANG Xiangshi;YU Qin;KUANG Shaodan(Neonatology Dongfang People's Hospital,Dongfang,Hainan 572600,China;不详)
出处
《中国微生态学杂志》
CAS
CSCD
2023年第9期1076-1078,共3页
Chinese Journal of Microecology
关键词
呼吸窘迫综合征
肠道菌群
相关性
Neonatal respiratory distress syndrome
Gut microbiota
Correlation
