摘要
异黄酮类化合物的基本母核为3-苯基色原酮,具有良好的药理作用。对2013—2022年国内外报道的新异黄酮类化合物的化学结构进行综述;归纳其氢谱核磁共振及碳谱核磁共振数据的特点,对其δH-2位进行了重新归属;并对其抗肿瘤、抗氧化、抑菌等方面的药理作用进行总结,以期为异黄酮类化合物的开发应用提供理论参考。
3-phenylchromone is the basic nucleus of isoflavonoids,which has good pharmacological effects.This paper has reviewed the chemical structures of isoflavonoids newly reported at home and abroad from 2013 to 2022.The characteristics of its hydrogen spectrum and carbon spectrum were summarized,and theδH-2 of isoflavonoids was reassigned.In addition,the pharmacological effects of anti-tumor and anti-oxidation activities,and bacteriostasis were summarized,so as to provide theoretical reference for the development and application of isoflavonoids.
作者
张恒
涂红英
熊思蕾
刘彩虹
杨蒂
韩越
王雄龙
何卿
欧阳文
ZHANG Heng;TU Hongying;XIONG Silei;LIU Caihong;YANG Di;HAN Yue;WANG Xionglong;HE Qing;OUYANG Wen(School of Pharmacy,Hunan University of Chinese Medicine,Changsha,Hunan 410208,China;Key Laboratory ofModern Research of TCM,Colleges and Universities of Hunan Province,Changsha,Hunan 410208,China;HunanTime Sun Pharmaceutical Co.Ltd.,Yongzhou,Hunan 410116,China;The Second Integrated Chinese and WesternMedicine Hospital of Hunan University of Chinese Medicine,Liuyang,Hunan 410300,China;Liuyang Hospital ofChinese Medicine,Liuyang,Hunan 410300,China)
出处
《湖南中医药大学学报》
CAS
2023年第10期1925-1931,共7页
Journal of Hunan University of Chinese Medicine
基金
湖南省自然科学基金项目(2021JJ30500)
湖南省中医药科研计划项目(2021060)
湖南省研究生科研创新项目(CX20210709,2023CX72)
湖南省大学生创新创业训练计划项目(湘教通[2021]197号)
湖南省普通高等学校教学改革研究项目(HNJG-2021-0577)
湖南中医药大学学位与研究生教育教学改革研究课题(2021JG04)
湖南中医药大学中药学一流建设学科(校行科字[2018]3号)。
关键词
异黄酮
化学成分
化学位移
抗肿瘤
药理作用
isoflavonoids
chemical constituent
chemical shift
anti-tumor
pharmacological effects
