摘要
目的了解某院患者输血前乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)、人类免疫缺陷病毒(HIV)、梅毒(TP)感染状况及探讨感染标志物检测的临床意义。方法选取2020年1月—2022年12月收治500例因手术、血液成分异常、重大外伤等情况拟输血患者作为研究对象,在输血前所有患者行四项感染标志物检查,即乙型肝炎表面抗原(HBsAg)、丙型肝炎病毒抗体(HCV-Ab)、人类免疫缺陷病毒抗体(抗HIV)、梅毒螺旋体特异性抗体(抗TP)。记录患者四项指标阳性率检验结果。结果(1)男性患者HBsAg、HCV-Ab、抗HIV、抗TP四项指标总阳性率高于女性患者(P<0.05);(2)女性患者中,0~20岁、21~40岁、41~60岁、>60岁4个年龄段HBsAg、HCV-Ab、抗HIV、抗TP四项指标总阳性率分别为1.61%、13.11%、10.34%、3.08%,21~40岁相较于其他年龄段均更高(P<0.05);(3)男性患者中,0~20岁、21~40岁、41~60岁、>60岁4个年龄段HBsAg、HCV-Ab、抗HIV、抗TP四项指标总阳性率分别为3.17%、20.31%、18.33%、10.45%,21~40岁相较于其他年龄段均更高(P<0.05)。(4)儿科四项指标感染率最低,而传染科、肿瘤科、肾内科四项指标感染率较高。结论输血前对患者进行HBsAg、HCV-Ab、抗HIV、抗TP四项指标检查,有利于识别输血患者感染情况,对于减少医疗纠纷、预防医务人员职业暴露及减少院内感染具有重要意义。
Objective To understand the infection status of hepatitis B virus(HBV),hepatitis C virus(HCV),human immunodeficiency virus(HIV)and Treponema pallidum(TP)in patients before blood transfusion in a hospital and to explore the clinical significance of detection of infection markers.Methods 500 patients who were scheduled to undergo blood transfusion due to surgery,abnormal blood composition and major trauma from January 2020 to December 2022 were selected as the research subjects.All patients underwent 4 infection markers examinations before blood transfusion,including hepatitis B surface antigen(HBsAg),hepatitis C virus antibody(HCV-Ab),human immunodeficiency virus antibody(anti-HIV)and Treponema pallidum specific antibody(anti-TP).The detection results of positive rates of four indicators were recorded.Results(1)The total positive rate of HBsAg,HCV-Ab,anti-HIV and anti-TP in male patients was higher than that in female patients(P<0.05).(2)Among female patients,the total positive rates of HBsAg,HCV-Ab,anti-HIV and anti-TP of four age groups of 0-20 years old,21-40 years old,41-60 years old and>60 years old were 1.61%,13.11%,10.34%and 3.08%respectively,and the total positive rate of 21-40 years old was higher in than that in other age groups(P<0.05).(3)Among male patients,the total positive rates of HBsAg,HCV-Ab,anti-HIV and anti-TP were 3.17%,20.31%,18.33%and 10.45%at 0-20 years old,21-40 years old,41-60 years old and>60 years old.The total positive rate of 21-40 years old was higher than in other age groups(P<0.05).(4)The infection rate of the four indicators was the lowest in department of pediatrics while the infection rate of the four indicators was higher in department of infectious diseases,department of oncology and department of hemodialysis.Conclusion The examination of HBsAg,HCV-Ab,anti-HIV and anti-TP before blood transfusion is conducive to the identification of infection in patients with blood transfusion,and is of great significance for reducing medical disputes,preventing occupational exposure of medical personnel and lowering nosocomial infection.
作者
周召瑜
钟雪梅
欧阳丽娟
ZHOU Zhao-yu;ZHONG Xue-mei;OUYANG Li-juan(Department of Blood Transfusion,Longnan No.1 People's Hospital,Longnan,Jiangxi,341700,China)
出处
《中国血液流变学杂志》
CAS
2023年第2期281-284,295,共5页
Chinese Journal of Hemorheology
关键词
输血
乙型肝炎病毒
丙型肝炎病毒
人类免疫缺陷病毒
梅毒
临床意义
blood transfusion
hepatitis B virus
hepatitis C virus
human immunodeficiency virus
treponema pallidum
clinical significance
